该反应过程存在显著的底物抑制。
针对底物抑制现象 ，提出了菌种驯化和流加甘油发酵两种解决途径。
Both approaches of bacteria improvement and fed batch fermentation to avoid substrate inhibition were proposed.
用l-酪氨酸作底物，测定了牛磺酸对酪氨酸酶的非竞争性抑制。
The noncompetitive inhibition of taurine on tyrosinase was determined with L - Tyrosine as substrate.
产物竞争性抑制的存在将增加载体颗粒内的底物浓度，对效率因子的影响较小。
The effects of competitive product inhibition are shown to increase the substrate concentration in the carrier, and, additionally, to increase the effectiveness factors slightly.
底物和产物对反应有抑制作用。
研究了具有底物和产物抑制以及代谢过量特征的微生物连续培养过程的数学模型。
Mathematic model was studied in continuous cultivation of microorganisms with overflow metabolism, whose growth was inhibited by substrates and products.
目的以谷胱甘肽-S -转硫酶(GST)为模型，探讨有产物抑制时用积分法分析酶反应过程测定底物量的可靠性。
Objective To investigate the reliability of the integrated method for kinetic assay of substrate in the presence of product inhibition using glutathione-S-transferase (GST) as model.
在前三种底物条件下，当高底物浓度时，L-苯丙氨酸表现出反竞争性抑制作用；低底物浓度时，则呈现激活作用。
As the former three substrates were employed, at high substrate concentration, L-Phe inhibited the enzyme uncompetitively and activated the enzyme at low substrate concentration.
竞争性抑制竞争性抑制剂与底物竞争酶的活性部位，降低酶的约束力基板的可能性，并观察到的反应速度放缓。
Competitive INHIBITION Competitive inhibitors compete with substrate for an enzyme's active site, lowering the enzyme's likelihood of binding substrate and slowing the observed reaction velocity.
这三种蛋白酶具有相似的底物特异性和抑制剂特性。
These three proteases are similar in substrate and inhibitor specificity.
结果表明，萃取发酵可以减轻产物对微生物的抑制作用，提高初始底物浓度，增加发酵速率。
The results showed that the extractive fermentation could reduce the product inhibition on microbes, increase the initial glucose concentration, and increase the fermentation rate.
最终产物抑制剂与它调节的酶的底物在结构上无相似之处。
The end product inhibitor has no structural similarity to the substrate of the enzyme it is regulating.
酶底物动力学分析表明，马桑内酯对该酶的抑制属非竞争性抑制。
The enzyme-substrate kinetic analysis indicated that it was the noncompetitive inhibition.
用L—酪氨酸作底物，测定了银杏叶提取物对酪氨酸酶的非竞争性抑制作用。
The noncompetitive inhibition of EGb on tyrosinase was determined with L-Tryosine substrate.
PTEN通过对PIP3和FAK等底物的去磷酸化作用，抑制肿瘤细胞生长、侵润和迁移，促进凋亡。
PTEN inhibits tumor cell growth, invasion and migration, promotes apoptosis through dephosphorylating its substrates such as PIP3 and FAK.
认识药物代谢的酶学基础，了解药酶的常见底物、诱导剂和抑制剂，合理选用同类药品，能避免有害药物代谢性相互作用的发生。
The adverse drug interactions can be avoided by knowing the enzymology basis of drug metabolism, common substrates, inductors, inhibitors involved and using the same kind of drugs rationally.
而唾液酸是唾液酸苷酶的底物，对唾液酸苷酶具有抑制作用，与很多种病毒的感染和传播关系密切。
Acetylneuraminic acid, the substrate of neuraminidase, which display a inhibitory effects on neuraminidase, has a close relationship with the infection and spread of many kinds of virus.
本文就这些蛋白酶的种类，底物及其抑制剂的作用作一综述。
In this paper, these types of protease, inhibitors of the substrate and its role reviewed.
混合抑制剂，也可以结合底物的酶-底物复合物后。
Mixed inhibitors can also bind after substrate to the enzyme-substrate complex.
动力学研究表明s - 24酶抑制剂抑制糜蛋白酶，对底物酪蛋白、血红蛋白的关系均为竟争性抑制。
Kinetic analysis revealed that the inhibition on chymotrypsin by S-24 enzyme inhibitor is competitive with respect to the substrate.
混合抑制剂不直接绑定在活动现场，因此没有阻止底物结合，而是在活动现场近端或远端的网站可以绑定。
Mixed inhibitors do not bind directly in the active site, and therefore do not block substrate binding, but instead bind at sites that can be proximal or distal from the active site.
目的探讨人白细胞弹性蛋白酶(HLE)与其底物反应的最适条件，建立一种高通量的HLE抑制剂体外筛选模型。
ObjectiveTo explore the most suitable reaction condition for human leukocyte elastase (HLE) and its substrates, so as to establish a high-throughput in vitro screening model for HLE inhibitor.
以谷胱甘肽S转硫酶（GST）为模型，探讨有产物抑制时用积分法分析酶反应过程测定底物量的可靠性。
To investigate the reliability of the integrated method for kinetic assay of substrate in the presence of product inhibition using glutathioneStransferase(GST) as model.
优化产物抑制常数可使此积分法所得反应终点产物吸收对剩余底物变化不敏感。
The optimization of product inhibition constant conferred to resistance to the variation of residual substrate concentration on the estimation of maximal product absorbance.
优化产物抑制常数可使此积分法所得反应终点产物吸收对剩余底物变化不敏感。
The optimization of product inhibition constant conferred to resistance to the variation of residual substrate concentration on the estimation of maximal product absorbance.
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