目的分析左向右分流型先天性心脏病左心室功能。
Objective To analyse function of left ventricle among patients with left-right shunt congenital heart disease.
左向右分流型心脏病发生肺动脉高压标志病情已进入严重阶段。
Left to right shunt heart diseases with pulmonary hypertension (ph) indicates a severe phase.
方法：20例左向右分流先心病患儿术中取肺、骨骼肌活检。
METHODS: Lung and skeletal muscular tissue were obtained from 20 children with left-to-right shunt by biopsy during operation.
其机制是与左向右分流造成左右心室复极的不同步、合并右心室肥大有关。
Mechanism is a blood shunt from left to right lead to desynchrony of the ventricular repolarization, also with the right ventricular hypertrophy.
常见的左向右分流先天性心脏病及发绀型先天性心脏病的病理生理，手术的意义及时机。
Pathophysiology of common left-to-right shunt congenital heart disease and cyanotic congenital heart disease; the significance and timing of surgery.
目的建立左向右分流所致肺动脉高压大鼠模型，了解高肺血流量对肺血管胶原代谢的影响。
Objective To establish a rat model of pulmonary hypertension induced by left-to-right shunt and explore the influence of high pulmonary blood flow on pulmonary vascular collagen remodeling.
急性支气管肺炎、支气管哮喘、左向右分流型先天性心脏病患儿的血浆ANF含量明显增高。
However, children with acute bronchopneumonia, asthma, or left to right shunt congenital heart diseases have significantly higher plasma ANF levels than healthy children.
方法：选取合并重度肺动脉高压左向右分流型先天性心脏病患儿38例，于矫治手术中取肺活检。
Methods: Lung biopsies were taken in the corrective operations in 38 young children suffered from left to right shunt congenital heart defects associated with severe pulmonary hypertension.
ES是由长期左向右分流引起，该左向右分流诱导了肺血管改变，导致分流方向逆转即右向左分流。
Es is caused by long-standing left-to-right shunt lesions, which induce pulmonary vascular changes, resulting in reversal of the shunt flow.
目的：探讨左向右分流型先天性心脏病(CHD)患者血浆内皮素(ET - 1)浓度的变化及其临床意义。
Objective: to study the alteration and clinical significance of plasma endothelin-1 (ET-1) concentration in patients with left to right shunt congenital heart disease (CHD).
用彩色多普勒血流会聚法对20例动脉导管未闭患者的左向右分流率F进行测定，并根据F值计算出动脉导管的横截面积A。
The left to right shunt rate (f) and the transverse sectional area of ductus arteriosus (a) were calculated by color Doppler flow convergence method in 20 patients with patent ductus arteriosus.
结论血浆BNP和CT ？1水平能较好地反映左向右分流型CHD病儿的心功能状态，血浆CT ？ 1水平随肺动脉压力升高而升高。
Conclusion the plasma levels of ct? 1 and BNP can better reflect cardiac status in children with left? To? Right shunt CHD, and the ct? 1 levels increase along with the rising of PAP.
结论血浆BNP和CT ？1水平能较好地反映左向右分流型CHD病儿的心功能状态，血浆CT ？ 1水平随肺动脉压力升高而升高。
Conclusion the plasma levels of ct? 1 and BNP can better reflect cardiac status in children with left? To? Right shunt CHD, and the ct? 1 levels increase along with the rising of PAP.
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