结论用基因工程抗体技术制备抗体是可行的。
CONCLUSION Preparing antibodies by genetic engineered antibody technology is feasible.
目的制备高活性的可溶性抗人血管生长素噬菌体基因工程抗体。
Objective To prepare the high effective and soluble genetic engineering antibody of anti-human angiogenin.
而要研制基因工程抗体,鼠源性抗体可变区基因的克隆与测序是关键。
To generate the recombinant antibodies, the key point is the cloning and the sequencing of the VH and VL genes from antibody secreting hybridoma cell line.
汪静。李官成。童永清鼻咽癌人源抗独特型基因工程抗体的原核表达及鉴定。
Wang J. Li GC Expression, purification and identification of the human anti-idiotypic single chain antibodies against nasopharyngeal carcinoma in E. coli.
基因工程抗体融合蛋白比传统的化学交联的抗体融合蛋白具有更多的优越性。
Genetically engineered antibody fusion proteins have more advantages over traditional chemical crosslinking antibody fusion proteins.
基因工程抗体融合蛋白比传统的化学交联的抗体融合蛋白具有更多的优越性。
Genetically engineered antibody fusion proteins have more advantages over traditional chemical crosslinking antibody fusion prot...
基因工程抗体融合蛋白比传统的化学交联的抗体融合蛋白具有更多的优越性。
Antibody fusion protein can be particularly used to prepare the immuno directed drug. Genetically engineered antibody fusion proteins have more advantages over traditional chemical crosslink...
结论:基因工程抗体在疾病的诊断和预防,特别是治疗方面有广阔的应用前景。
Conclusion: Genetically engineered antibodies have a potential application in diagnosis and prevention, especially treatment of the diseases.
文章评述了这一领域的最新进展,同时也讨论了工程抗体的免疫原性和亲和力。
This review summarized recent developments in this field, also discussed the immunogenicity and affinity of engineered antibodies.
快速研制一种可用于紧急预防SARS病毒感染的基因工程抗体预防制剂迫在眉睫。
It is urgent to develop a specific SARS virus-targeted antibody preparation for emergent prophylaxis and treatment of SARS virus infection.
结论:弱化表达载体中DHFR的表达,可提高MTX对工程抗体表达的增加效果。
CONCLUSION: MTX induced-increase of recombinant antibody production in CHO cells can be increased by weakening the expression of DHFR gene.
目的构建人源性抗hfrs病毒基因工程抗体基因的表达载体,为其进一步在真核细胞中表达奠定基础。
Aim to construct anti HFRS virus human engineering antibody expression vectors and then to express it in eukaryotic cells.
结论:利用噬菌体抗体库技术筛选可得到与破伤风外毒素特异性结合的人抗破伤风类毒素基因工程抗体。
Conclusion: Human genetic engineering antibody, which is able to react specifically to tetanus toxin, is obtained through screening phage antibody library.
抗肿瘤抗生素与抗体工程技术的结合可以作为新的技术平台,制备一系列的针对不同靶点的、用于治疗癌症的抗体靶向药物。
The integration of antitumor antibiotic and antibody engineering can serve as new technical platform for manufacture of a series of various target-specific antibody-based drugs for cancer therapy.
目的:用基因工程技术生产大量重组CB,为研究CB的生物学特性和制备CB抗体供临床检测作准备。
Aims: To obtain enough recombinant CB by using genetic engineering technique for studying its biological characteristics and obtaining its antibodies for clinical detection.
结论用E1工程蛋白检测e1抗体具有较高的灵敏度和特异性。
Conclusion Detection of anti HCV E1 by engineered E1 protein is sensitive and specific.
目前主要研究方向是水生动物的抗体及蛋白质工程。
Current researches are on antibody and protein engineer of aqua cultural animals.
针对抗体毒副作用进行的基因工程改造取得一定进展,目前已经有许多CD3抗体进入临床试验。
The genetically engineered antibodies toward the two drawbacks have made a great breakthrough, and several engineered CD3 antibodies have been used in clinical trials.
膜受体是一类膜蛋白,而全长的膜蛋白很难通过基因工程获得,这给制备该类蛋白的抗体增加了难度。
Membrane receptors belong to a kind of membrane proteins, the full length protein of which is hard to be expressed in vitro.
目的构建表达P30蛋白抗原表位的重组质粒及工程菌,获得纯化的P30蛋白抗原表位,用于检测弓形虫特异性抗体。
Objective To construct a recombinant plasmid containing P30 gene of Toxoplasma gondii and obtain recombinant protein Methods P30 gene fragment was amplified from genomic DNA of T.
目的构建表达P30蛋白抗原表位的重组质粒及工程菌,获得纯化的P30蛋白抗原表位,用于检测弓形虫特异性抗体。
Objective To construct a recombinant plasmid containing P30 gene of Toxoplasma gondii and obtain recombinant protein Methods P30 gene fragment was amplified from genomic DNA of T.
应用推荐