目的：完善和规范基因剔除小鼠技术体系的关键技术环节，建立一套高效的嵌合体制备体系。
Objective: To establish a highly efficient production system of chimeras by perfecting and normalizing the key steps of technology system of gene knockout mice.
嵌合体由两种或两种以上有不同基因结构的组织所构成的有机体，由于突变、嫁接或来自不同合子的细胞群体相混合而产生。
An organism consisting of two or more tissues of different genetic composition, produced as a result of mutation, grafting, or the mixture of cell populations from different zygotes.
遗传上混合的胚胎甚至被科学家都称作凯米拉(基因嵌合体)，源自古希腊神话的一种狮头，羊身，蛇尾的吐火的妖怪。
Genetically mixed embryos are referred to even by scientists as chimeras, after a monster from ancient Greek mythology. Perhaps that shows a lack of public-relations nous.
本文对禽类胚胎生物工程技术，包括禽类胚胎体外培养技术、禽类嵌合体技术和禽类基因转移技术的研究进行了综述。
The studies on biological engineering technology of embryo in birds, including the in vitro culture, chimera and transgenic birds are summarized in the essay.
外源基因(双链dna)作为外显子可能整合在一条染色体上的不同dna链上，转基因鱼的第一代为嵌合体。
Foreign gene (double stranded DNA) is maybe integrated in different DNA strand of the same chromosome as an exon. The first generation of transgenic fish is Mosaic.
造血干细胞混合嵌合体是指两个不同基因型个体的骨髓造血干细胞共存的一种状态。
Mixed hematopoietic chimerism is a state in which bone marrow hematopoietic stem cells from two genetically different individuals coexist.
本研究旨在探讨非清髓异基因外周血造血干细胞移植(NAPBSCT)后造血嵌合体的临床意义。
The aim of this study was to analyze the hematopoietic chimerism after non-myeloablative allogeneic peripheral blood stem cell transplantation (NAPBSCT).
介绍一些具体方案，包括建立异基因骨髓嵌合体、阻断T细胞活化第二信号和转基因技术诱导移植免疫耐受。
Some experimental protocols were introduced including mixed chimerism of allogeneic bone marrow, blockade of co-stimulation signal and transgene technology for transplantation tolerance induction.
介绍一些具体方案，包括建立异基因骨髓嵌合体、阻断T细胞活化第二信号和转基因技术诱导移植免疫耐受。
Some experimental protocols were introduced including mixed chimerism of allogeneic bone marrow, blockade of co-stimulation signal and transgene technology for transplantation tolerance induction.
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