灌胃给药8周后分别测定其对大鼠肾质量、肾功能及尿白蛋白排泄量的影响。

After 8 weeks of administration, the weight of rat kidney, renal function and the excretion of urine albumin were measured.

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结果缬沙坦治疗组较糖尿病非治疗组尿白蛋白排泄量明显减少（P＜001），血肌酐水平下降（P＜005），肾脏肥大指标改善（P＜005）。

Results Serum creatinine level ( P< 0.05), urinary albumin excretion and kidney hypertrophy index ( P< 0 01) of valsartan treated group were significantly lower than those of diabetic untreated group.

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结果缬沙坦治疗组较糖尿病非治疗组尿白蛋白排泄量明显减少（P＜001），血肌酐水平下降（P＜005），肾脏肥大指标改善（P＜005）。

Results Serum creatinine level ( P< 0.05), urinary albumin excretion and kidney hypertrophy index ( P< 0 01) of valsartan treated group were significantly lower than those of diabetic untreated group.

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