“据悉,有10至12尼古丁受体表达表面上的各种细胞,”陈博士解释。
"It has been known that there are 10 to 12 nicotine receptors that express on the surface of various cells," Chen explained.
这项发现预示了一种利用尼古丁受体来预防帕金逊症的新型方法是有可能实现的。
These findings suggest that it may be feasible to develop novel therapies for Parkinson's disease that target nicotine receptors, particularly the alpha-7 nicotine receptor.
在你停止吸烟时,你的尼古丁受体不再被启动,因而你无法得到你习惯得到的那么多多巴胺。
When you stop smoking, and your nicotine receptors stop being activated.
大脑中的尼古丁受体有15个亚基,这些亚基以不同方式结合形成多种受体行使不同功能。
The nicotine receptor in the brain has 15 subunits; they can combine in a multitude of ways to form different receptors with different jobs.
就此,15号染色体上成为研究热点的这一区域存在另外两种编码尼古丁受体的基因,提示实际情况将更为复杂。
That, and the fact that the region of chromosome 15 under scrutiny has two other nicotine-receptor genes in it, suggests the situation may indeed be more complex.
也可能使用处方药:戒必适,针对的是大脑的尼古丁受体,同时,人们已经发现抗抑郁剂耐烟盼也能减少你对尼古西的渴望。
Prescription drugs are also available: Champix targets the brain's nicotine receptors, while the antidepressant Zyban has been found to reduce cravings for nicotine.
目的观察氟中毒对神经细胞中尼古丁受体亚单位蛋白和基因表达水平的影响及氟中毒引起尼古丁受体功能改变的发生机制。
Objective to investigate the influence of fluorosis on nicotinic acetylcholine receptors (nAChRs) in protein and gene levels in SH-SY5Y cells and the mechanism of the receptor modification.
我们不知道为什么尼古丁受体表达各种组织器官的所有细胞表面,但我们知道尼古丁是一个重要的神经递质在中枢神经系统。
We do not know why nicotine receptors express in all the cell surfaces from various tissue origins, but we do know that nicotine is an important neuron transmitter in the central nervous system.
随后尼古丁控制了脑细胞受体,并释放出多巴胺——大脑中感觉良好的化学成分,能给人带来愉悦和舒适的感觉。
Then the nicotine grabs hold of receptors on brain cells and releases dopamine, the brain's feel-good chemical, bringing feelings of pleasure and comfort.
该小组发现当几代老鼠的受体功能被改变时,对尼古丁的需求就会增加—它们的大脑没有接收到停止信号。
The team found that when rats were genetically modified to alter the receptor function, the amount of nicotine they consumed escalated greatly -- their brain wasn’t getting the “stop” message.
然而有一个特别明显的候选对象,就是alpha4beta2,因为该受体在尼古丁在大脑中的反应中扮演了主要角色。
However, there is one particularly strong candidate, alpha4beta2, because it plays a major role in nicotine's actions in the brain.
在这一情况下,编码一种受体分子基因的内部发生了变异——当这一受体发出信号时,尼古丁就与之结合。
In this case, the variation happens inside a gene for one of the receptor molecules that nicotine attaches itself to when it produces its buzz.
科学家发现小鼠吸收尼古丁后导致了斯里兰卡肉桂碱2型受体(RYR2)的表达。
The scientists found that nicotine administration to mice induces the expression of a gene called type 2 ryanodine receptor (RyR2).
选择性的CB1受体阻滞剂通过作用该受体,具有治疗肥胖、酒精依赖、尼古丁成瘾、认知障碍以及胃肠道系统疾病等作用。
Selective CB1-R antagonists have potential in the treatment of a number of diseases, such as obesity, alcohol dependence, nicotine addiction, cognitive disorders, and gastrointestinal disorders.
尼古丁可与其中任意一种受体相结合进而激发一系列反应:一些可导致香烟成瘾,另一些可导致血压升高或放松感。
Nicotine can bind to each combination and spur a cascade of distinct events; some lead to the addictive properties of cigarettes, others to an increase in blood pressure or a feeling of relaxation.
尼古丁可与其中任意一种受体相结合进而激发一系列反应:一些可导致香烟成瘾,另一些可导致血压升高或放松感。
Nicotine can bind to each combination and spur a cascade of distinct events; some lead to the addictive properties of cigarettes, others to an increase in blood pressure or a feeling of relaxation.
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