目的研究联合运用狂犬病毒糖蛋白基因重组腺病毒与同一抗原核酸疫苗对小鼠的免疫效果。
Objective To investigate the immune response of mice primed by DNA particle bombing and boosted by immunization with replication-defective adenoviral recombinant bearing rabies glycoprotein gene.
目的：构建表达小鼠轮状病毒（EDIM）EW株VP7基因的重组腺病毒，以在小鼠模型上研究轮状病毒的免疫保护机制。
Objective:To construct a replication defective recombinant adenovirus expressing murine rotavirus(EDIM)EW strain VP7to recruit it in studies on the protective immunization of rotavirus.
目的：克隆人和小鼠的活化t细胞表达与分泌调节基因(RANTES基因)并分别构建腺病毒表达载体。
Objective: to clone the human and murine origin RANTES genes and construct the adenoviral expression vectors.
目的：探讨小鼠心脏移植中，通过在体外保存期间对供心进行灌注，进行重组腺病毒基因转染的方法及效率。
AIM: To establish a method of in vitro donor heart perfusion in murine cardiac transplantation during preservation and apply it in adenovirus mediated gene transfection for donor heart.
同时观察重组腺病毒对荷瘤小鼠的治疗效应。
Meanwhile, the therapeutic effect of the recombinant adenovirus was also observed in tumor-bearing mice.
结论：小鼠心脏移植保存期间体外灌注可应用于腺病毒基因转染等移植物处理过程。
CONCLUSION: in vitro perfusion during graft cold preservation is feasible for adenovirus mediated gene transfection.
结论：小鼠心脏移植保存期间体外灌注可应用于腺病毒基因转染等移植物处理过程。
CONCLUSION: in vitro perfusion during graft cold preservation is feasible for adenovirus mediated gene transfection.
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