方法：采用小鼠淋巴瘤细胞试验（MLA）和小鼠骨髓微核试验（MNT）。
Method: Mouse lymphoma assay(MLA) and mouse bone marrow micronucleus test(MNT) were used.
在之前的研究中，我们发现马兜铃酸是一种强致突变剂，对小鼠淋巴瘤细胞有显著的细胞毒性和致突变作用。
In the previous study, we have found that AA is a potent mutagen which can induce significant cytotoxic and mutagenic effects on mouse lymphoma cells.
目的研究b 71基因转染小鼠el4淋巴瘤细胞的致瘤性，为制备基因转染瘤苗提供实验依据。
Objective to study the Oncogenicity of rat EL4 lymphoma cell transfected with gene B71 and to provide experimental basis for preparing tumor vaccine by transfected gene.
目的探讨用转粒细胞巨噬细胞集落刺激因子(GM CSF)基因瘤苗，联合白介素12 (IL 12)治疗小鼠t细胞淋巴瘤的方法。
Objective To study the method of immunotherapy against t cell lymphoma by tumor cells transfected by GM-CSF gene combined with interleukin 12 (IL-12).
方法：给正常野生型C57BL/6小鼠皮下接种小鼠淋巴瘤EL4细胞，建立荷EL4肿瘤的小鼠模型。
METHODS: Mouse lymphoma EL4 cells were inoculated subcutaneously into wild type C57BL/6 mice (immune-competent mice).
他们将原癌基因诱导的淋巴瘤移植到野生型小鼠，然后在淋巴瘤细胞启动p53表达。
They transplanted Myc-driven lymphoma cells into wild-type mice and then turned on p53 expression in the lymphoma cells.
他们将原癌基因诱导的淋巴瘤移植到野生型小鼠，然后在淋巴瘤细胞启动p53表达。
They transplanted Myc-driven lymphoma cells into wild-type mice and then turned on p53 expression in the lymphoma cells.
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