丹尼斯的成功最终导致了严重的问题。
小镇镇长Damien Thiery说这导致了严重的问题。
The town's mayor Damien Thiery says it is causing real problems.
丹尼斯的成功最终导致了严重的问题。80年代中期，批评家说他控制了市场。
Dennis's success eventually caused more serious problems. In the mid-1980s, critics accused him of strong-arming the market.
他最近有了一项重大发现——孤独是一个严重的社会问题，它会导致抑郁甚至犯罪，但可以用一种聪明的方法加以阻止。
He has recently made a significant discovery—loneliness is a serious social problem that can contribute to depression and even crimes, but it can be prevented in a clever way.
现在他们已经导致了巨大的严重的问题，这可能毁掉他们公司——而且可能毁掉花生工业。
Now they've caused a mammoth problem that could destroy their company - and it could destroy the peanut industry.
即使缺陷导致了安全问题，它导致的安全问题的严重性可能会更低。
Even if a bug causes a security problem, the problems it causes are likely to be less severe.
但问题依然存在，因为偏爱男孩的文化偏见，导致了萨达拉和印度其他地区出现了严重的性别比例失衡问题。
Problems persist, such as a sharp gender imbalance in Satara and many other regions of India because of a cultural bias toward having sons.
许多陷入严重问题的项目在后期被取消，从而导致重大的经济损失，错失了商机。
Many projects seriously in trouble are also cancelled at a fairly late stage, thus having incurred significant economic loss as well as lost opportunity costs.
电视普及，盗版问题严重，导致了电影业的衰落。
The popularity of television and the serious problem of piracy have contributed to the decline of movie industry.
对于Silverlight团队来说，这是个让人难堪的问题，因为问题的严重程度导致人们开始嘲笑他们了。
This is a rather sore subject for the Silverlight team, as the severity of the problem has caused them quite a bit of ridicule.
但如果大量排汗时没有足够的水量补充，身体会进入失水状态，严重了会导致小或大的身体问题。
However, if you perspire a lot without drinking enough fluids, your body can dehydrate, and this can cause both minor and major health problems.
这里是苏丹和这两个国家的交通运输的中转站，从某种意义上来说，这也导致了卡萨拉州成为该国艾滋病问题最严重的地区之一。
Partly because Kassala is a trans-shipment point between those two countries and Sudan, the state has one of the biggest HIV problems in the country.
伍晓鹰表示，严重的数据问题并不令人意外地妨碍了对中国生产率情况的正确衡量，从而导致对生产率的估计出现了很大的矛盾之处。
'Correctly measuring China's productivity has, not surprisingly, been obstructed by severe data problems that have resulted in widely contradictory productivity performance estimates,' Mr. Wu said.
众所周知，持续增加的污染导致了像全球变暖这样严重的问题，而且还将直接威胁到我们的生活质量。
As we all know, increasing pollution causes serious problems such as global warming and even directly threatens the quality of our lives.
空气污染导致了很多严重的问题。
然而，网络交往中严重泛滥的道德失范问题导致了人类文明转型过程中的混乱，加重了当代人类的道德危机。
While nonstandard morality widespread the network communication, which causes the confusion during the human civilization transform and also aggravates the 'contemporary human moral crisis.
医疗安全问题导致了严重的经济后果。
Patient safety problems lead to serious economic consequences.
睡眠严重不足会不仅会增加儿童肥胖的几率，也容易导致其他的一些健康问题。然而，研究员说，选择在周末或是假期“补眠”可以有效减少工作日时因为被剥夺了睡眠所带来的后果。
Too little sleep puts kids at risk of obesity and other health conditions, but "catch-up" sleep on weekends and holidays can mitigate the effects of weekday sleep deprivation, researchers say.
这家英法合资公司一直在抓紧时间解决问题。公司说，导致几辆列车瘫痪的原因是：粉状降雪渗透到保护过滤器中，引发引擎出现了严重故障。
The Anglo-French company rushed to fix the problem it said caused several of its trains to break down: powdery snow that seeped through protective filters and triggered a major engine malfunction.
而在中国北方尘沙天气中，颗粒物是一大健康问题，导致了北京本身就严重的空气污染进一步恶化。
Particulates are a big health concern in dusty northern China, and they add to the notoriously bad air pollution in Beijing itself.
然而，近年来中国企业，特别是上市公司的会计行为异化问题非常严重，导致了严重的会计信息质量问题。
However, endless accounting behavior alienations took place in firms especially listed companies of China in recent years had caused lots of serious accounting information problems.
由于各种抗生素的广泛使用，细菌耐药问题日趋严重，导致了铜绿假单胞菌产生了很强的耐药性而且多重耐药，铜绿假单胞菌通过多种途径产生耐药。
The varieties of antibiotics are used widely and the bacterial drug resistance appears greatly. P. aeruginosa have acquired a great resistance and multiple resistance by many methods.
但是在路面设计时结构设计与材料设计相脱离的问题比较严重，从而导致了沥青路面的早期损坏。
But in the pavement design, the structure design and the material design are seriously separated, which lead to the early damage in asphalt pavement.
但是，随着抗生素的广泛应用，特别是持续、不当使用，在临床上出现了严重的耐药问题，耐药性产生的直接后果是严重影响临床疗效，甚至导致治疗失败。
With the extensive use of the antibiotics, especially abuse, the serious problem of bacterial resistance has happened in clinic, which results in a decrease in curative effect, and even no effect.
煤矸石山的露天堆存导致了严重的环境问题和社会问题，已成为煤矿区环境治理的重要课题。
Coal waste piles have led to serious environmental problems and social problems, which has become an important issue for coal mining area environment.
资本结构的不合理导致了我国国有上市公司严重的内部人控制问题，而内部人控制又加深了资本结构的缺陷。
Unreasonable capital structure of listed companies has led to a serious state of internal control problems, and enhance internal control and capital structure of the defects.
资本结构的不合理导致了我国国有上市公司严重的内部人控制问题，而内部人控制又加深了资本结构的缺陷。
Unreasonable capital structure of listed companies has led to a serious state of internal control problems, and enhance internal control and capital structure of the defects.
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