为解决胶原酶免疫原性，采用经氯甲酸对硝基苯酯活化的单甲氧基聚乙二醇来修饰胶原酶。
In order to overcome the immunogenicity of collagenase, the enzyme was modified with monomethoxypolyethylene glycol 5000 (mPEG) activated by p nitrophenyl chloroformate.
为解决胶原酶免疫原性，采用经氯甲酸对硝基苯酯活化的单甲氧基聚乙二醇来修饰胶原酶。
In order to overcome the immunogenicity of collagenase, the enzyme was modified with monomethoxypolyethylene glycol 5000 (mPEG) activated by p nitrophenyl chloroformate.
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