目的:探讨反义寡核苷酸对胆囊癌细胞端粒酶活性的影响及对胆囊癌细胞生长增殖的作用。
Objective: To study the antisense oligonucleotide mediated inhibition on telomerase activity and cell proliferation of GBC-SD cell.
目的:利用纳米载体增强端粒酶反义寡核苷酸对肝脏肿瘤细胞生长的抑制作用。
Objective: To investigate the growth inhibition of antisense oligonucleotides of telomerase on liver tumor cell enhanced by albumin nanoparticles.
目的:探讨端粒酶逆转录酶(TERT)的反义寡核苷酸(A SODN)对甲状腺癌(TC)细胞凋亡的影响。
AIM: to investigate the effect of antisense oligonucleotides (ASODN) encoding telomerase reverse transcriptase (TERT) mRNA on thyroid carcinoma (TC) cell apoptosis.
成功的反义显像要求反义寡核苷酸易被细胞摄取、耐核酸酶、杂交稳定、标记简单。
The requirements for ideal antisense imaging include easy intakeing by cells, convenient labelling, stable hybridization and the tolerance against nuclease.
目的检测针对端粒酶rna的反义寡核苷酸对鼻咽癌hne - 1细胞株生长的影响。
Objective To investigate the effects of AS-ODN targeting against telomerase RNA on the growth of HNE-1 cell line.
目的:观察酰基辅酶a:胆固醇酰基转移酶1 (ACAT1)反义寡核苷酸对泡沫细胞(FC)形成的影响。
AIM: To study the effect of acyl coenzyme a: cholesteryl acyltransferase 1 (ACAT1) antisense oligonucleotides on the formation of foam cells (FC).
结果端粒酶正义寡核苷酸与反义寡核苷酸一样可抑制鼻咽癌cne1和CNE2 Z细胞的生长,且呈剂量和时间依赖性。
RESULTS SODN inhibited the growth of CNE1 and CNE2Z cells as well as ASODN, and presented dose and time dependent manner.
结果端粒酶正义寡核苷酸与反义寡核苷酸一样可抑制鼻咽癌cne1和CNE2 Z细胞的生长,且呈剂量和时间依赖性。
RESULTS SODN inhibited the growth of CNE1 and CNE2Z cells as well as ASODN, and presented dose and time dependent manner.
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