目的合成异核苷掺入寡核苷酸并考察它们与互补序列的结合能力。
AimTo synthesize ribonucleoside-incorporated oligonucleotides and investigate their binding abilities with complementary sequences.
结果以HIV寡核苷酸探针作为核心序列，在其一端或两端连接上多种通用序列标签（UST）构建新型探针。
Results HIV oligo probes used as core target sequences were linked with several universal sequence tags (USTs) at their one or both ends, and were then printed onto the slides.
本发明的经修饰寡核苷酸作为治疗剂施用，并且与所针对的RNA分子内的互补序列杂交。
Modified oligonucleotides of the invention are administrated as therapeutic agents, and hybridize to complementary sequences within targeted RNA molecules.
根据肺炎支原体细胞粘附素蛋白质的基因保守区两侧序列，设计并合成一对变性寡核苷酸引物L2R2，用于以鸡毒支原体S6株基因组DNA为模板的PCR反应。
A pair of degenerate oligonucleotide primers named L2R2were synthesized according to conserved regions of the cytadhesin proteins from M. pneumonias. MG-S6DNA were used as model in L2R2 primered PCR.
目的设计一种带有通用序列标签的寡核苷酸探针以应用于寡核苷酸芯片点样的质量控制。
Aim To design an universal sequence-tagged oligonucleotide probes for spot quality control of oligonucleotide microarrays.
目的设计一种带有通用序列标签的寡核苷酸探针以应用于寡核苷酸芯片点样的质量控制。
Aim To design an universal sequence-tagged oligonucleotide probes for spot quality control of oligonucleotide microarrays.
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