由于移植物抗宿主病病情的严重性,临床医生在治疗中,往往缺乏细致诊断,就使用大剂量的类固醇抑制免疫细胞的反应。
Because of the severity of GVHD, clinicians often begin treatment — high doses of steroids to suppress the immune response — in the absence of a concrete diagnosis.
镜下,移植物抗宿主反应是说明“程序性细胞死亡”或单个细胞坏死(即调亡)过程的最好例子。
Microscopically, graft versus host disease is one of the best examples of a process called "apoptosis" or single cell necrosis.
宿主的免疫系统可能反应过激并且杀死太多细胞,这可能是这个病毒更具致病力的关键因素。
The host's immune system may be overreacting and killing off too many cells, and that may be a key contributor to what makes this virus more pathogenic.
新的研究发现了一种通过操纵宿主细胞内的一种常见信号通路来破坏早期宿主免疫反应并提高致病性的以前未知的酶反应机制。
New research identifies a previously unknown enzymatic mechanism that subverts the early host immune response and promotes pathogenicity by manipulating a common signaling pathway in host cells.
处死后,进行脊髓切片病理分析移植性免疫细胞存在情况,宿主的免疫反应情况,组织保留情况,胶质瘢痕形成情况和移植治疗效果。
After sacrifice, spinal cord sections were histologically analyzed for presence of graft-derived immune cells, host immune response, tissue sparing, glial scar formation, and grafting efficacy.
结论:宿主细胞再活化反应性可用于临床辅助判断癌前病变预后和针对性监控的指标。
Conclusion: the host cell reactivation is likely to be a helpful indicator for predict prognosis of cancer for the individuals with highly genetic sensitivity to cancer.
处死后,用特殊的抗体和髓鞘尼氏染色法处理脊髓切片,分析骨髓基质细胞移植物大小、组织保留情况、宿主免疫反应和神经胶质疤痕形成情况。
After sacrifice, spinal cord sections were analyzed for MSC graft size, tissue sparing, host immune response, and glial scar formation, using specific antibodies and Nissl-myelin staining.
HIV - 1整合酶(IN)通过依赖金属离子的两步反应将病毒DNA整合入宿主细胞中。
HIV-1 integrase (in) integrates viral DNA into host cells through two steps metal ions-dependent reactions.
病毒感染宿主细胞是病毒致病的关键所在,病毒感染细胞需要与其受体相结合,介导其与细胞的膜融合反应。
Infection of host cells by virus is the key for the virulence, virus particles infect the host cells by binding to cellular receptor and by the receptor-mediated membrane fusion reaction.
巨噬细胞在宿主防御反应中起了重要的作用,是天然免疫应答的主要参与者。
Macrophages play a significant role in the host defense mechanism. And it is the key participants in the innate immune response.
一氧化氮是一种重要的巨噬细胞免疫效应分子,它参与免疫调节和宿主防御反应。
Nitric oxide is an important effector molecule of macrophages that is involved in immune regulation and host defense.
目的分析异体造血干细胞移植前加用抗T淋巴细胞球蛋白(ATG)预防移植物抗宿主反应(GVHD)的疗效。
Objective To analyze effects of antithymocyte globulin(ATG) in preventing the occurrence of graft-versus-host disease(GVHD) in allogeneic stem cells transplantation.
结论:提示皮肤组织的细胞免疫反应在血吸虫减毒尾蚴免疫的宿主抗攻击感染保护性免疫中起重要作用。
CONCLUSION: Cellular immune response in the skin of the mice immunized with UV-attenuated cercariae might play an important role in the protective immunity against challenge infection.
从输入的血液中清除外来的白细胞可以减少外来白细胞与宿主免疫系统发生负反应的机会。
Removing the foreign white cells from transfused blood reduces the chances of a negative reaction by the host immune system.
提示恶性肾肿瘤细胞中存在活化的细胞间粘附分子和血管细胞粘附分子基因,并可能影响肿瘤与宿主间的免疫反应。
These results suggest that there are active genes of ICAM-1 and VCAM-1 on malignant renal tumors and might be able to effect the host immune reaction.
此为移植物抗宿主反应,供者淋巴细胞攻击了宿主组织。
This is an example of graft versus host disease in which donor lymphocytes attack host tissues.
巨噬细胞是调控宿主免疫和炎症反应的重要细胞,因此它对生物材料的响应性对认知材料-宿主反应有重要作用。
Macrophage is a central cell type in directing host inflammatory and immune processes; thus, its response to biomaterials is extremely important in understanding material-mediated host response.
巨噬细胞是调控宿主免疫和炎症反应的重要细胞,因此它对生物材料的响应性对认知材料-宿主反应有重要作用。
Macrophage is a central cell type in directing host inflammatory and immune processes; thus, its response to biomaterials is extremely important in understanding material-mediated host response.
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