他说:“如果这种检测能够在皮疹显现之前预测移植物抗宿主病的发病,那将是非常有价值的。”
"If this test could predict the onset of GVHD before the rash develops, it could be extremely valuable, " he says.
由于移植物抗宿主病病情的严重性,临床医生在治疗中,往往缺乏细致诊断,就使用大剂量的类固醇抑制免疫细胞的反应。
Because of the severity of GVHD, clinicians often begin treatment — high doses of steroids to suppress the immune response — in the absence of a concrete diagnosis.
除了患者病情复发,移植物抗宿主病是接受骨髓细胞移植病人死亡的主要原因。
Apart from relapse of a person's disease, GVHD is the principal cause of death in patients who have received donated bone marrow.
12个月之后,第一组移植物抗宿主病死亡率和并发症发病率是第二组的三倍。
After 12 months, three times as many patients in the high-elafin group had died from GVHD and its complications than in the low-elafin group.
镜下,移植物抗宿主反应是说明“程序性细胞死亡”或单个细胞坏死(即调亡)过程的最好例子。
Microscopically, graft versus host disease is one of the best examples of a process called "apoptosis" or single cell necrosis.
肝、肠、皮肤是公认的移植物抗宿主病(GVHD)靶器官,肺可能也是潜在的GVHD靶器官。
The liver, skin and intestine are the classic GVHD target organs and lungs may be a potential GVHD target organ.
目的探讨TJU103对小鼠同种异基因造血干细胞移植模型移植物抗宿主病(GVHD)是否起预防作用。
Objective To explore the role of TJU103 in preventing graft-versus-host disease (GVHD) after allogeneic stem cell transplantation in mice.
移植物抗宿主疾病反映的是胆小管内黄棕色的胆汁淤积,同时肝实质慢性炎细胞浸润。
The graft versus host disease here is marked by yellow-brown collections of bile in the canaliculi, as well as chronic inflammatory cells within the liver parenchyma.
目的探讨异基因造血干细胞移植(HSCT)后表现在肾脏的慢性移植物抗宿主病(GVHD)的临床及病理特点。
Objective to investigate the clinicopathologic characteristics of renal chronic graft versus host disease (GVHD) after allogeneic peripheral blood hematopoietic transplantation (HSCT).
目的综述异种移植物抗宿主反应(GVHD)动物模型的研究现状、检测方法及进展情况。
Objective To review the current condition, test method and progress of the animal model of xenograft versus host disease (xeno GVHD).
目的分析异体造血干细胞移植前加用抗T淋巴细胞球蛋白(ATG)预防移植物抗宿主反应(GVHD)的疗效。
Objective To analyze effects of antithymocyte globulin(ATG) in preventing the occurrence of graft-versus-host disease(GVHD) in allogeneic stem cells transplantation.
本文介绍异基因骨髓移植后,移植物抗宿主病(GVHD)的皮肤病损组织学特点。
The histological features of skin lesion of graft-versus-host disease (GVHD) following allogeneic bone marrow transplantation were described.
目的了解异种移植物抗宿主病(GVHD)的组织学特点,与同种GVHD的区别及异种脾脏移植的关系。
Objective To evaluate the histological characteristics of xenogeneic graft-versus-host disease(GVHD), and to differentiate it from the allogeneic GVHD.
目的探索雷帕霉素在慢性移植物抗宿主病治疗中的作用。
Objective To explore the effect of rapamycin in treatment of refractory chronic graft-versus-host-disease(cGVHD).
移植物抗宿主病主要出现在病程早期皮肤表现损害多样化。
There are cutaneous manifestations and they often occur in the early stage.
临床若无移植物抗宿主病出现,3~6个月逐渐减量至停药,单倍型移植者适当延长。
The drug doge was reduced and stopped gradually after 3-6 months, which could be prolonged for haplotype grafter .
目的:初步探讨小鼠同基因型移植物抗宿主病(SGVHD)的发生机制,为研究移植物抗白血病效应奠定基础。
Objective: To primarily explore the immunological mechanism of SGVHD and provide a platform for study of graft-versus leukemia.
目的探讨输注同种脾细胞建立小鼠输血相关的移植物抗宿主(TA -GVHD)模型及其特点。
Objective To develop transfusion associated graft vs host disease (TA-GVHD) model by infusing allogeneic splenocytes.
结论慢性移植物抗宿主模型类似人类狼疮性肾炎,是良好的狼疮肾炎模型。
Conlusion The mouse model of chronic GVHD, which is alike to human lupus nephritis, can be used as a good model of lupus nephritis.
移植物抗宿主反应(GVHR)和移植脾亢是脾移植的两个棘手问题。
There are two knotty problems in spleen transplantation, graft versus host reaction (GVHR) and graft hypersplenism, which are very dangerous and uncontrolled.
结果与B6WT组比较,B6 CCR5KO组小鼠以更快的速度死于急性移植物抗宿主疾病(GVHD);
Results Compared to B6 WT group, B6 CCR5 KO group succumbed to acute GVHD at an accelerated rate.
此为移植物抗宿主反应,供者淋巴细胞攻击了宿主组织。
This is an example of graft versus host disease in which donor lymphocytes attack host tissues.
所述组合物和方法用于治疗自身免疫、炎症、过敏、哮喘、移植排斥、移植物抗宿主疾病、感染、脓毒、癌症和免疫缺陷。
The compositions and methods have use in the treatment of autoimmunity, inflammation allergy, asthma, graft rejection, graft versus host disease, infection, sepsis, cancer and immunodeficiency.
本发明的方法也可用于诱导对骨髓移植和其他器官移植物的耐受并抑制移植物抗宿主疾病。
The methods of the invention can also be used to induce tolerance in cases of bone marrow transplantation and other organ transplants and to inhibit graft-versus-host disease.
在不相干的捐赠者移植中,使用喷司他丁,他克莫司和微型甲氨蝶呤预防移植物抗宿主疾病:一项I/II期对照,适应性随机研究。
Prophylaxis of Graft-Versus-Host Disease in Unrelated Donor Transplantation With Pentostatin, Tacrolimus, and Mini-Methotrexate: A Phase I/II Controlled, Adaptively Randomized Study.
在不相干的捐赠者移植中,使用喷司他丁,他克莫司和微型甲氨蝶呤预防移植物抗宿主疾病:一项I/II期对照,适应性随机研究。
Prophylaxis of Graft-Versus-Host Disease in Unrelated Donor Transplantation With Pentostatin, Tacrolimus, and Mini-Methotrexate: A Phase I/II Controlled, Adaptively Randomized Study.
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