就目前而言，这是一个术语上的而非实质性的突破。
For the moment, it is a breakthrough of terminology more than substance.
结果造成物理学在很长时期内没有实质性的突破。
The result is that physics in a very long period of time has had no substantial breakthrough.
当然，奥巴马的出席不一定会给这些国际问题的解决带来什么实质性的突破。
Obama’s presence does not promise a sudden solution to the world’s problems.
目前在对微观组织研究方面，组织模型能够完整建立，但是在应用上一直未能有实质性的突破。
Currently, though an organizational model can be completely built in research on the microstructure, there has not been a breakthrough in the application.
而长期以来，一直困惑自由曲面精加工取得实质性突破的关键问题之一，就是加工工具的运动位姿控制问题。
But for a long time, one of the key questions which puzzled free surface precision machining obtaining substantive breakthrough, is machining tool's movement pose control problems and so on.
这是一个会有实质性突破的时候，你要为此做好准备并等待。
This is when the real nitty gritty happens and you've got to be ready and waiting.
过去由于受研究手段所限，对钢管连轧过程诸多问题，如金属流动、缺陷形成等的研究难以取得实质性突破。
As research methods limited, many problems such as metal flowing, defect forming have not been able to attain the significant breakthrough for steel tube con-rolling process.
过去由于受研究手段所限，对钢管连轧过程诸多问题，如金属流动、缺陷形成等的研究难以取得实质性突破。
As research methods limited, many problems such as metal flowing, defect forming have not been able to attain the significant breakthrough for steel tube con-rolling process.
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