但有关心肌缺血再灌注损伤的具体机制还未完全阐明。
But the exact mechanism of the reperfusion injury is not quite sure.
短暂缺氧血清剥夺再灌注后,存在低能量状态,且可完全恢复。
There existed a lower energy status after transient anoxia-serum deprivation and reperfusion and the lower energy status can resume the normal level.
自由基在继发性损伤中的具体机制尚未完全清楚,可能与缺血级联反应、缺血再灌注和细胞凋亡有关。
The mechanisms contributing to the brain damage have not yet been well clarified. The mechanisms may be related with ischemic cascade reaction, ischemic reperfusion and cell apoptosis.
方法:用离体大鼠心脏双冠状动脉分别灌流模型,将左冠状动脉灌流量减到原灌流量的5%,进行不完全缺血60分钟,再进行2小时再灌注。
Methods:Isolated rat heart was subjected to dual coronary perfusion model. The flow of the left coronary bed was reduced to 5% of basal flow for 60 min of ischemia and then reperfused for 2 hours.
方法:用离体大鼠心脏双冠状动脉分别灌流模型,将左冠状动脉灌流量减到原灌流量的5%,进行不完全缺血60分钟,再进行2小时再灌注。
Methods:Isolated rat heart was subjected to dual coronary perfusion model. The flow of the left coronary bed was reduced to 5% of basal flow for 60 min of ischemia and then reperfused for 2 hours.
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