建立首批醋酸奥曲肽的国家对照品。
目的设计并合成醋酸奥曲肽。
采用HPLC-MS法测定奥曲肽血药浓度。
奥曲肽植入物的整体安全性与奥曲肽类似物相似。
Overall safety of the octreotide implant and octreotide lar were similar.
目的：比较奥曲肽与加贝酯对急性胰腺炎的疗效。
AIM: To compare the effect of octreotide and gabexate in treating acute pancreatitis.
结论：奥曲肽是治疗急性消化道大出血的有效药物。
Conclusions: Octreotide is effective in the treatment of acute massive gastrointestinal hemorrhage.
目的探讨奥曲肽对胃癌术后vegf及肠功能的影响。
Objective To investigate the effects of octreotide on gastric cancer and intestinal function of VEGF.
目的研究槲皮素联合奥曲肽对人乳腺癌细胞增殖的影响。
Objective To study the combined effects of quercetin and octreotide on multiplication of human breast cancer cells.
孕酮联合奥曲肽对A549细胞的生长具有更强的抑制作用。
Progesterone enhances the ability of octreotide to inhibit the growth of A549 cells.
方法采用固相多肽合成法，使用逐步缩合的战略合成奥曲肽。
Method Octreotide was synthesized by the solid-phase peptide synthesis method and stepwise condensation strategy.
目的评价奥曲肽在治疗食管胃底静脉曲张破裂出血中的应用效果。
Objective To evaluate the effect of octreotide used in esophageal and gastric variceal bleeding patients.
结论奥曲肽是治疗非甾体类抗炎药致上消化道大出血的理想药物。
Conclusion Octreotide is an idea drug with treating upper alimentary canal massive hemorrhage.
结论：奥曲肽治疗上消化道大出血起效快，使用方便，无副作用。
Conclusion: Octreotide is quick to act, easy to use and has no side effects in the treatment of upper gastrointestinal hemorrhage.
按3：1比例随机分到6个月奥曲肽植入或每月奥曲肽类似物注射。
Randomization was in a 3:1 ratio to either 6-month octreotide implant or monthly octreotide LAR injections.
目的观察奥曲肽辅助肝动脉结扎(HAL)治疗大鼠肝内移植瘤的效果。
Purpose To investigate the effects of hepatic arterial ligation (HAL) combined with octreotide for transplanted cancer in rat liver.
目的探讨生长抑素类似物奥曲肽在垂体促甲状腺素瘤诊断和治疗中的作用。
Objective To evaluate the efficacy of octreotide in the diagnosis and treatment of pituitary thyrotropin-secreting adenoma.
目的观察奥曲肽和垂体后叶素序贯治疗食管静脉曲张破裂出血的疗效及副作用。
Objective Curative effect and side actions of octreotide and pituitrin were observed in the course of bleeding of esophageal varicose vein.
目的探讨奥曲肽预防ERCP术后胰腺炎和高淀粉酶血症的临床疗效和安全性。
Objective To study on the efficacy of Octreotide prophylaxis of post ERCP pancreatitis (PEP) and hyperamylasemia.
目的评价奥曲肽联合硝苯地平治疗肝硬化食管胃底静脉曲张破裂出血的临床疗效。
Objective To evaluate the effects of octreotide combined with nifedipine on esophageal and gastric varicose bleeding (EGVB).
生长抑素及其类似物如奥曲肽和伐普肽等在药理剂量下也可以引起内脏血管收缩。
Somatostatin and analogues such as octreotide and vapreotide also cause splanchnic vasoconstriction at pharmacological doses.
奥曲肽植入物植入后，血清奥曲肽浓度在8天内增加，并在14—28天到达峰值。
Serum octreotide concentrations after implant insertion increased within 8 days and peaked between day 14 and 28.
结论：奥曲肽对高氧诱导的小鼠视网膜新生血管有抑制作用，且具有剂量依赖性。
Conclusion: Octreotide can inhibit retinal neovascularization in the mouse, and with the increase in dose inhibition become more obvious.
孕酮联合奥曲肽抑制A549细胞生长的作用比奥曲肽单药更强（P<0.05）。
Progesterone combined with octreotide was superior to progesterone or octreotide alone in inhibiting the growth of A549 cells(P<0.05).
脸部潮热伴或不伴全身潮热是观察到的奥曲肽经动脉给药唯一的机体反应，呈一过性。
Facial hectic fever or whole body hectic fever seems to be the only and transient body reaction to octreotide given through artery.
目的探讨生长抑素类似物奥曲肽在垂体促甲状腺素(tsh)瘤诊断和治疗中的作用。
Objective To evaluate the efficacy of octreotide in the diagnosis and treatment of pituitary thyrotropin (TSH) -secreting adenoma.
结论奥曲肽联合内镜套扎术可以明显提高食管静脉曲张破裂出血的治疗效果和安全性。
Conclusion Octreotide in combination with endoscopic band ligation can significantly improve the therapeutic effect and safety for esophageal variceal bleeding.
目的：评价国产醋酸奥曲肽注射液治疗食管-胃底静脉曲张破裂出血的疗效和安全性。
Objective: To evaluate the efficacy and safety of domestic octreotide for injection in the treatment of acute esophageal and gastric variceal bleeding.
主要评价指标：在24周的治疗期间评估评估奥曲肽植入物的有效性、安全性和耐受性。
Main Outcome Measure: to evaluate the efficacy, safety, and tolerability of the octreotide implant during 24 weeks of treatment.
注射用生长抑素类似物奥曲肽已被证明治疗长期严重腹泻的糖尿病患者是有用的(1)。
Parenteral somatostatin analog octreotide has been shown to be useful in the treatment of severe long-standing diabetic diarrhea (1).
奥曲肽植入物常见的不良反应为腹泻和头痛，而奥曲肽类似物更常见的为胆囊炎和高血压。
Diarrhea and headache were more frequent with the implant, while cholecystitis and hypertension were more frequent with octreotide LAR.
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