目的考察奥扎格雷钠在国人中的药动学过程。
OBJECTIVE To study the pharmacokinetic profiles of ozagrel in healthy Chinese volunteers.
结论奥扎格雷钠可诱导CYP2D6酶的活性。
Conclusion Sodium Ozagrel can induce the activity of CYP2D6.
结论:奥扎格雷钠口服给药无明显的抗血栓作用。
Conclusion: Thrombosis can't be inhibited by Ozagrel Sodium through oral administration.
目的:通过口服给药研究奥扎格雷钠的抗血栓作用。
Objective: To study the antithrombotic function of Ozagrel Sodium through oral administration.
目的了解奥扎格雷对糖尿病足浅表溃疡愈合的影响。
Objective To assess the effect of ozagrel on superficial ulcer of diabetic foot.
目的:研究奥扎格雷钠注射液的细菌内毒素检查方法。
Objective: to study the method of testing bacterial endotoxin in the ozagrel sodium injection.
目的:探讨奥扎格雷钠对慢性肺心病急性加重期的疗效。
Objective: To investigate the effects of sodium ozagrel in the treatment of Cor Pulmonale in exacerbation period.
结论奥扎格雷钠注射液治疗脑梗死疗效确切,安全可靠。
Conclusions Sodium ozagrel was effective and safe for cerebral infraction.
目的:建立反相高效液相色谱法测定奥扎格雷有关物质。
OBJECTIVE a RP HPLC method was established to determine related substance in ozagrel.
目的观察奥扎格雷钠治疗椎基底动脉供血不足50例疗效。
Objective To observation the effect of treatment of 50 cases of vertebral basilar artery insufficiency (VBI) with Ozagrel.
结论方法简单、准确,可用于盐酸奥扎格雷片剂的含量测定。
Conclusion This method is simple, accurate and can be used to control the quality of Ozagrel Hydrochloride Tablets.
结论奥扎格雷钠治疗急性脑梗死效果良好,无明显不良反应。
Conclusion Ozagrel has definite clinical effect on treating acute cerebral infarction and less adverse reaction.
结果:丁咯地尔组疗效较好,奥扎格雷组和低分子肝素钙组次之。
Result: The effect of buflomedil group was better than ozagrel group and low molecular heparin calcium group.
目的观察奥扎格雷钠治疗急性脑梗死的疗效和对血液流变学的影响。
Objective To observe the curative effect and the rheological changes in treatment of acute cerebral infarction with sodium ozagrel.
目的观察前列地尔(PGE-1)联合奥扎格雷治疗急性脑梗死的疗效。
Objective To observe the clinical efficacy of PGE-1 combined with Ozagrel in treating acute cerebral infarction.
目的比较注射用奥扎格雷钠和川芎嗪治疗不稳定型心绞痛(UA)的疗效。
Objective to compare the therapeutic effects of sodium ozagrel and ligustrazine in the treatment of unstable angina pectoris (UA).
结论奥扎格雷钠和川芎嗪治疗不稳定型心绞痛,具有显著的抗心肌缺血作用。
Conclusion Sodium ozagrel and ligustrazine were shown to have notable effects to relieve myocardial ischemia in the treatment of UA.
目的:观察奥扎格雷钠、低分子肝素钠联合应用治疗进展性脑梗死的临床疗效。
AIM: To observe the clinical effect of combination therapy with ozagrel and low molecular weight heparin on progressive cerebral infarction.
结论奥扎格雷钠是改善脑血流,治疗急性脑梗死有效药物,有临床推广应用价值。
Conclusions Sodium ozagrel can improve the cerebral blood stream and is an effective medicine curing acute cerebral infarction. So it has the value of clinical application.
结论:奥扎格雷钠对脑血的保护作用可能与抑制C -Fos蛋白的表达有关。
Conclusion: the protective mechanism of Sodium Ozagrel for Injection is probably related to the inhibition of C-FOS gene expression.
结论银杏达莫、奥扎格雷钠联合治疗急性脑梗死,疗效显著,而且无出血等并发症。
Conclusion The combination of ginkgo-damole and ozagrel in treating acute cerebral infarction can produce good curative effects without causing bleeding.
奥扎格雷治疗组的基本痊愈率、显著进步率、总有效率明显高于对照组(均P<0.05)。
The rates of cure, significant development and total validity were all higher than those in the control group(all P<0.05).
两组患者治疗有效率的比较:阿加曲班组有效率91.67%。 奥扎格雷钠组有效率87.50%。
The effective rate of the two groups: The argatroban group is 91.67% and theozagrel group is 87.50%.
结论奥扎格雷钠可通过调节脑缺血后脑组织中et - 1、CGRP的水平,减轻神经细胞损伤的发生。
Conclusion Ozagrel sodium may alleviate the nerve cell damage by modulating the levels of ET-1 and CGRP in brain tissues after cerebral ischemia.
比较二组患者奥扎格雷钠治疗前血小板活性指标和临床指标的差异及奥扎格雷钠治疗后对观察组血小板活性指标和临床指标的影响。
Platelet activity and clinic factors of two groups before therapy of Ozagrel sodium were compared. Influence of Ozagrel sodium on Platelet activity and clinic factors of observation group was studied.
比较二组患者奥扎格雷钠治疗前血小板活性指标和临床指标的差异及奥扎格雷钠治疗后对观察组血小板活性指标和临床指标的影响。
Platelet activity and clinic factors of two groups before therapy of Ozagrel sodium were compared. Influence of Ozagrel sodium on Platelet activity and clinic factors of observation group was studied.
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