本课题主要目的是研究天王补心丸中桔梗舟楫作用的物质基础及其作用机制。
The present study is to elucidate the material basis and mechanisms of Radix Platycodi's vessels-like action.
抗惊厥试验结果：天王补心丸SP825体积分数为0.2和0.5乙醇洗脱部分均能够明显延长戊四唑所致小鼠阵挛性抽搐的潜伏期（P<0.05）。
Pentylenetetrazole induced eclampsia: Both SP825 0.2 and 0.5 alcohol fraction could remarkably prolong the latency of clonic convulsion induced by pentylenetetrazole( P< 0.05).
抗惊厥试验结果：天王补心丸SP825体积分数为0.2和0.5乙醇洗脱部分均能够明显延长戊四唑所致小鼠阵挛性抽搐的潜伏期（P<0.05）。
Pentylenetetrazole induced eclampsia: Both SP825 0.2 and 0.5 alcohol fraction could remarkably prolong the latency of clonic convulsion induced by pentylenetetrazole( P< 0.05).
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