• 目的探索简化单一密度梯度建立快速纯化大鼠胰岛细胞的方法。

    Objective To establish an rapid and simple discontinuous density gradient method for purification of islet cells from rat pancreas.

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  • 目的研究素对磺脲类降糖药刺激胰岛细胞分泌胰岛作用影响机制

    Objective to study the effect and mechanism of amylin upon oral sulfonylurea drugs and its action to stimulate the islet cell secretion of insulin in rats.

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  • 应用体外单层培养大鼠胰岛细胞检测不同浓度复方细胞胰岛素分泌、胰岛细胞增殖影响。

    The secretion function of the islet cell and its proliferation in different concentrations of the compound were measured.

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  • 结论:GLP鄄1促进大鼠胰岛细胞胰岛基因表达蛋白的分泌,对大鼠胰岛细胞有明显的促增殖作用

    Conclusion: GLP-1 can not only increase the insulin gene expression and insulin secretion, but also stimulate the proliferation of islet cells.

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  • 大鼠,SSLI细胞集中分布胰岛周边部,较少看到胞质突起。

    In rat, pig and ox pancreas, the SSLI cells mainly distribute at the periphery of the islets, cytoplasmic processes were rarely seen.

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  • 结果HAP1大鼠胰腺内选择性表达胰岛内分泌细胞

    Results HAP1 was selectively distributed in the endocrine cells of pancreatic islets.

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  • 目的探讨胰岛细胞联合移植治疗糖尿病效果以及胎肝细胞移植诱导糖尿病受者免疫耐受可行性

    Objective to study the effect of combined transplantation of pancreatic islets and hepatocytes on the treatment of diabetic rats and the possibility on hepatocytes inducing islet allograft tolerance.

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  • 结果正常盐水对照组比较,海洛因依赖大鼠胰岛SS-IR细胞免疫染色增强平均灰度降低,差异有显著性。

    Results: The immunological staining was obviously stronger, and mean grey degree was remarkably lower in SS-IR cells of rats in heroin dependent group than that in rats of normal control group.

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  • 目的研究运动对高糖高脂饮食诱导胰岛抵抗大鼠脂肪细胞葡萄糖转运蛋白4GLUT4)的影响

    Objective To investigate the effect of exercise on glucose transporter 4 (GLUT4) in adipocyte of rats with insulin resistance induced by diets.

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  • 目的探讨罗格列酮胰岛抵抗大鼠骨骼肌细胞葡萄糖转运蛋白4 (GLUT4)转位影响

    Objective To investigate effects of rosiglitazone on glucose transport-4 (GLUT4) protein translocation in skeletal muscle of insulin resistance rats.

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  • 目的研究供体凋亡细胞输注胰岛移植胰岛移植物功能影响

    Objective to observe the influence of transfusion of donor apoptotic cells on the function of islet grafts in rat islet transplantation.

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  • 目的研究运动链脲佐菌素所致糖尿病大鼠骨骼肌细胞葡萄糖运载体4 (GLUT4)基因表达胰岛受体结合的影响

    Objective: to investigate the effect of the exercise on glucose transporter4 (GLUT4) gene expression and insulin binding in streptozotocin induced diabetic rat skeletal muscle.

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  • 采用新生大鼠胰岛离体培养方法,观察五肽胃泌素(G-5)IL-1B胰岛B细胞分泌抑制影响

    The effect of pentagastrin (G-5) on interleukin-1B(IL-lB) inhibited insulin secretion in culturednewborn rat islet B-cells were observed.

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  • 目的观察大鼠实验性损伤期间胰岛a、B细胞变化

    Objective To observe the changes of A-and-B-cells of rats pancreatic islets during experimental brain injury.

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  • 目的探讨葛根素对高糖高脂饮食诱导胰岛抵抗脂肪细胞葡萄糖转运蛋白4 (GLUT4)表达水平及其转位机制影响

    AIM: To investigate the effects of puerarin on expression and translocation of glucose transporter 4 (GLUT4) in adipocyte of rats with insulin resistance induced by diets.

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  • 目的研究供体凋亡细胞输注大鼠胰岛移植胰岛移植物功能影响

    To investigate the impacts of cold ischemia preservation time and histocompatibility on the activity of islet cells during the islet transplantation.

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  • 结论胰岛大鼠灌注心肌损伤具有保护作用保护机制可能与抑制细胞凋亡自由基作用有关

    Conclusion Insulin has a protective effect against myocardial ischemia and reperfusion injury in rat, the protective mechanism involves antiapoptotic and antioxide free radical effect of insulin.

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  • 观察高血糖状态下大鼠骨髓是否存在胰岛细胞

    Objectives:( 1 ) To observe whether rat bone marrow harbors islet-like cells in hyperglycemic state.

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  • 证实胰岛原代培养前体脂肪细胞增殖分化明显促进作用。

    The results demonstrated that the promotion of insulin on proliferation and differentiation of the rat preadipocyte's primary-culture was significant.

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  • 证实胰岛原代培养前体脂肪细胞增殖分化明显促进作用。

    The results demonstrated that the promotion of insulin on proliferation and differentiation of the rat preadipocyte's primary-culture was significant.

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