• 方法:羟脯氨酸法、间接酶联免疫吸附法(ELISA测定博莱霉素A6(BLMA6诱发纤维化模型组织胶原含量及合成,阿利新测定其糖胺多糖(GAG)含量;

    METHODS: Hydroproline determination and ELISA were used for measuring the content of collagen, Alcian blue assay for BLM-A6 induced glycosaminoglycan (GAG) in the lung tissues (rats, mice).

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  • 结果大鼠实验性纤维化模型成功;

    Results: The rat model of pulmonary fibrosis was established.

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  • 方法采用大鼠油酸尾静脉注射制作急性损伤后纤维化模型观察红霉素对损伤组织中中性粒细胞聚集自由基干预作用

    Methods: Model of fibrosis of lung with injection by oil-acid to rat, observed the effect of erythromycin to neutrophil and oxygen-free radical.

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  • 方法首先建立大鼠百草枯中毒致纤维化动物模型

    Methods: Erect a paraquat-induced pulmonary fibrosis animal model first.

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  • 方法首先建立大鼠百草枯中毒致纤维化动物模型

    Methods: Erect a paraquat-induced pulmonary fibrosis animal model first.

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