事实上，这一事件已经变成一个大问题，我认为这件事表明一个事实，即种族问题仍然是困扰我们社会的一个方面。
The fact that this has become such a big issue I think is indicative of the fact that race is still a troubling aspect of our society.
这本书没有回答的一个大问题是，究竟为什么麦道夫变成了一个坏蛋。
The big question that the book fails to answer is why Mr Madoff became a villain at all.
有点像抗生素：只有你大量服用抗生素的时候，抗药性才变成一个大问题。
So it's a bit like antibiotics: Only if you have excessive use of antibiotics, does resistance become a major problem.
你需要细心处理那些小问题，以免它们演变成大问题。
The main idea is to take care of small issues now before they turn into major problems.
这是一个很可怕的想法，并且没有合法的行为来确保这不会变成一个大问题。
It's a scary thought and there's really no legal action that can be taken to ensure that this will not be made into an issue.
尤其是，他们时常不注意整体维护以及那些需要轻微修补的地方，而这些地方很容易变成大问题。
In particular, they too often fail to pay attention to maintenance and minor repairs, repairs that can easily become major problems.
记住有规律的量自己的体重。如果你注意到你的体重在增加，马上行动起来。不要让小问题变成大问题。
Remember to weigh yourself regularly. If you notice your weight increasing, take action immediately. Don't let a minor lapse become a major problem.
但是，一旦你忽略了它们或放任不管，它们就会变成大问题。
But, when you neglect them or let them sit, they become big ones.
由于同时解决所有问题的挑战性比较大，所以我们可能会把这些问题变成一个相对简单的大问题。
Because it's daunting to try and tackle several issues at once, we may try to roll these problems up into a less-complex Über-Problem.
当问题确实发生的时候，作业队能做出迅速的、精明的决定，并避免小事件变成大问题。
When problems do occur, the team can make rapid, informed decisions and prevent minor occurrences from becoming major problems.
传感器帮助识别小问题—在他们变成大问题之前。
"The sensors help identify the small problems — before they become big problems," Rantz said.
哈佛大学的安东尼·塞挈进行了一项投票调查，称环境问题在过去十年中变成了公众关心的一大问题。
Environmental issues have been major public concerns for over a decade, says Anthony Saich of Harvard University, which has conducted polls.
保险盒防止小问题变成大问题。
The fuse box can prevent that small problems become big problems.
大部分的问题都是从小事开始的，不要让小问题变成大问题。
如果你没意识到这点，那么这种奉献将会变成一个大问题。
If you are not aware of this, then giving becomes a great problem.
我认为这将会演变成一个大问题。
如果垃圾邮件变成了一个大问题，只要删除这个帐户，创建一个新的帐户，并且在你的基本资料中将电子邮件地址更改为一个新的地址。
If spam becomes too much of a problem, simply delete this account, create a new one, and change thee-mail address in your profile to the new address.
然而，如果小问题不在早期就得到讨论和解决，那么它们就能变成大问题。
Small problems can become big ones, however, if they are not discussed and dealt with early on.
然而，如果小问题不在早期就得到讨论和解决，那么它们就能变成大问题。
Small problems can become big ones, however, if they are not discussed and dealt with early on.
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