目的：研究分煎与混煎对大承气汤的影响。
Objective: To study the effect of dividual decocting and admixture decocting on Major Qi Infusing Decoction.
摸索血清样品制备方法，建立大承气汤的血中移行成分指纹图谱。
Then testing the preparation methods of serum sample and establishing the chromatographic fingerprint of blood transitional components of Dachengqi decoctions.
方法：分别测定了大承气汤分煎液与混煎液的浸膏重量、番泻甙a、辛弗林及柚皮甙的含量。
Methods: By determining the extract weight the contents of Sennoside a, Synephren and Naringin in dividual decoction and admixture decoction of Major Qi Infusing decoction.
大承气汤能阻止细胞色素C释入胞浆，从而阻断凋亡信号进一步传导，保护脑出血后神经元。
Dachengqi decoction has the effect of preventing the release of cyt-C into cell plasm thus to prevent and block the further transduction of apoptosis signal and protect the neurons after ICH.
研究表明：建立的方法准确、可靠，可用于大承气汤物质基础的研究和其中成药开发时的质量控制。
The established method is accurate and repeatable, and can be used for the study on the chemical material of this formula and the evidence for quality control of traditional Chinese drugs.
采用正交设计法，以腹泻频度为指标，研究大承气汤的组成，以直观分析法和方差分析法分析实验结果。
The composition of Dachengqi decoction was studied with orthogonal design and with the frequency of diarrhea as the target of treatment.
体外实验表明，去芒硝大承气汤具有抑制内毒素对肺泡巨噬细胞过度诱生TNF、IL-1、IL-6的作用；
Experimental results showed that Dachengqi Decoction (DT) without Mirabilite could inhibit the excessive inducing effect of LPS on TNF, IL 1, IL 6 of pulmonary macrophage in vitro.
目的：探讨大承气汤对内毒素“二次打击”致急性呼吸窘迫综合征(ARDS)的防治作用，为中西医结合防治呼吸道疾病提供有效依据。
AIM: to investigate the effect of Dachengqi decoction (DD) on the acute respiratory distress syndrome (ARDS) in rat model induced by endotoxin "two-hit".
目的：探讨大承气汤对内毒素“二次打击”致急性呼吸窘迫综合征(ARDS)的防治作用，为中西医结合防治呼吸道疾病提供有效依据。
AIM: to investigate the effect of Dachengqi decoction (DD) on the acute respiratory distress syndrome (ARDS) in rat model induced by endotoxin "two-hit".
应用推荐