按照已有的酶活性中心的金属-氨基酸侧链配位和空间关系，设计合成多齿配体，并使配体和金属离子通过配位作用形成配合物。
They are designed according to the special relations and coordination of metal-amino acid side chain in the active centre in known enzymes.
在此基础上研究作为DNA结构探针和抗癌试剂的过渡金属多吡啶配合物与多聚核苷酸dna的相互作用，既有一定的理论意义，又有重要的应用价值。
On this basis, the DNA binding study of transition metal polypyridyl mixed-ligand complexes as DNA structural probe and antitumor reagent has some theoretical meaning and important application value.
在此基础上研究作为DNA结构探针和抗癌试剂的过渡金属多吡啶配合物与多聚核苷酸dna的相互作用，既有一定的理论意义，又有重要的应用价值。
On this basis, the DNA binding study of transition metal polypyridyl mixed-ligand complexes as DNA structural probe and antitumor reagent has some theoretical meaning and important application value.
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