多药耐药性是化疗失败的主要原因。
Multidrug resistance (MDR) is one of the principal causes of failure in tumor chemotherapy.
肿瘤的多药耐药性是导致临床化疗失败最主要的原因。
The1 main reason of the failure in the cancer clinical chemotherapy is multidrug-resistance.
目的多药耐药性是导致急性白血病化疗失败的主要原因。
Objective Multidrug resistance can eventually result in the chemotherapy failure of acute leukemia.
目的：建立高效、稳定的人膀胱癌多药耐药性细胞模型。
Objective: To establish highly effective and stable multidrug resistance (MDR) bladder cancer cell line.
药物递送系统是克服肿瘤多药耐药性(MDR)的一种新策略。
Drug delivery system (DDS) is a novel approach to overcome multidrug resistance (MDR) in tumors nowadays.
结论雄黄可以逆转MCF7/ADM细胞的多药耐药性，并呈剂量依赖性；
Realgar can down regulate the expression of mdrl. mrp and bcrp in MCF 7/ADM cells.
目的综述近五年来多药耐药性p糖蛋白作用于药物肠道吸收过程的研究进展。
Objective To review the development of the key role of P-glycoprotein (P-gp) in the intestinal absorption of drugs during the past five years.
在许多国家，艾滋病毒加快了结核病流行，同时多药耐药性也日益成为一大威胁。
HIV is fuelling TB epidemics in many countries and multi-drug resistance is a growing threat.
两株耐药细胞对5-氟尿嘧啶、甲氨蝶呤产生了耐药，具有多药耐药性的特点；
Two cell lines with the characteristics of multi-drug resistance resistant to 5-fluorouracil and methotrexate;
但由于水溶性差、易产生多药耐药性和毒性较强等缺点限制了它们在临床上的应用。
However, their therapeutic use is often hindered by problems such us poor water solubility, acquired drug-resistance and strong toxicity.
目的：研究卡维地洛对人膀胱癌耐药细胞株BIU-87/ADM的多药耐药性逆转作用。
Purpose:To study the reversal effects on multidrug resistance in multidrug-resistent bladder cell lines BIU-87/ADM.
1967年报道了首例对青霉素相对不敏感的肺炎球菌，到1981多例多药耐药性肺炎球菌被报道。
In 1967 there were the first report of pneumococci that were relatively insensitive to penicillin and by 1981, there were cases of multiple drug resistance.
近年研究发现容积调控性氯通道与肿瘤细胞的增殖、侵袭、迁移、凋亡及多药耐药性等恶性生物学行为有关。
In recent years, it has been realized that volume-regulated chloride channels are closely associated with proliferation, invasion, migration, apoptosis and multi drug resistance of tumor cells.
这方面的进展代表着在这个复杂疾病处理上的一个突破。肝癌具有多药耐药性，但研究证明这种分子靶向对其治疗是有效的。
This advancement represents a breakthrough in the management of this complex disease, and proves that molecular targeted therapies can be effective in this otherwise chemo-resistant tumor.
目的探讨金克-槐耳颗粒是否能逆转人乳腺癌MCF-7/A细胞对阿霉素（ADM）的多药耐药性（MDR）及其逆转机制。
Objective The aim of this study is to discuss whether the Jinke plaster can reverse the MDR of the breast cancer cell strian MCF-7/A to ADM or not and the mechanism.
结论5 F 11 -DXR对敏感靶细胞的杀伤作用较d XR明显增强，并可有效逆转耐药靶细胞对DXR的多药耐药性。
Conclusion 5f11-dxr can remarkably increase the cytotoxicity of DXR to the sensitive target cells and even effectively reverse the drug-resistant cell lines to DXR.
形成耐多药结核或广泛耐药结核的第二个途径是患者自身的结核产生耐药性。
A second way of developing MDR-TB or XDR-TB is when a patient's own TB develops resistance.
耐多药结核描述至少对两种主要一线抗结核药物-异烟肼和利福平具耐药性的结核菌株。
MDR-TB (Multidrug Resistant TB) describes strains of tuberculosis that are resistant to at least the two main first-line TB drugs - isoniazid and rifampicin.
现在已有50多个国家报告出现广泛耐药结核病[2]。这是耐多药结核的一个分类，耐药性极高，结果也显著地更严重。
XDR-TB 2, a subset of MDR-TB of highly drug-resistant strains that have significantly worse outcomes, has now been reported in more than 50 countries.
现在已有50多个国家报告出现广泛耐药结核病[2]。 这是耐多药结核的一个分类，耐药性极高，结果也显著地更严重。
XDR-TB2, a subset of MDR-TB of highly drug-resistant strains that have significantly worse outcomes, has now been reported in more than 50 countries.
耐多药结核病是由对多数有效抗结核病药物（异烟肼和利福平）都具有耐药性的细菌引起的。
MDR-TB is caused by bacteria that are resistant to the most effective anti-TB drugs (isoniazid and rifampicin).
结核病的耐药性分成单耐药、多耐药、耐多药、严重耐多药这几个层次。
TB drug resistance is divided into single-drug resistance, multidrug resistance, MDR, MDR-serious levels of these.
采用流式细胞术检测骨髓细胞多药耐药蛋白P170的相对表达率，并分析P170表达阳性率与耐药性和性别间的关系。
The expression of multidrug resistance protein P170 in marrow cells was detected by flow cytometry, and the correlations of the expression of P170 with drug resistance and gender were analysed.
目的：了解当前结核病对一线及二线抗结核药物的耐药性及耐多药情况，为结核病防治提供依据。
Objective: To investigate the resistance status of Bacillus tuberculosis to anti?tuberculosis drugs of fist and second ranks in use, and so as to provide basic data for tuberculosis (TB)prevention .
本研究结果表明，鸡场大肠杆菌耐药性严重，且以多药耐药为主。
The result shows that antimicrobial resistance of bacteria was serious and mainly multi-drug resistance.
本研究结果表明，鸡场大肠杆菌耐药性严重，且以多药耐药为主。
The result shows that antimicrobial resistance of bacteria was serious and mainly multi-drug resistance.
应用推荐