多药耐药相关基因与蛋白的检测。
Detection of multidrug resistance-related genes and proteins.
目的建立人肺腺癌多药耐药细胞系。
Objective To establish a multidrug resistance cell line from human lung adenocarcinoma.
喉癌；多药耐药；免疫组化；预后。
Laryngeal carcinoma; Drug resistance; Immunohistochemistry; Prognosis.
目的寻找有效的多药耐药联合逆转剂。
Objective to develop effective combination of drug resistance modulators.
多药耐药是近年来乳腺癌治疗研究的困扰之一。
Multidrug resistance (MDR) is one of curses on the study of breast cancer therapy in recent years.
目的：探讨消化道肿瘤的多药耐药机制和逆转策略。
Aims: To study the multi-drug resistance mechanism of digestive tract tumors and its reverse strategy.
本文对难治性癫痫近年来有关多药耐药现象进行综述。
In this paper, the recent progresses about the multi-drug resistance in the treatment of intractable epilepsy were summarized.
因此，乳腺癌多药耐药蛋白有望成为一种新的治疗靶点。
So, the breast cancer resistance protein will be the new therapeutic target.
目的探讨流式细胞术在阿霉素多药耐药研究中的特殊意义。
Objective to evaluate the significance of flow cytometry (FCM) in the analysis of multi drug resistance of doxorubicin.
肿瘤化疗失败的主要原因是多药耐药（MDR）的产生。
Multidrug resistance (MDR) of cancer cells is a major cause of failure in chemotherapy.
目的探讨CYP3A5基因与白血病细胞多药耐药的关系。
Objective To investigate if CYP3A5 gene is involved in the molecular mechanisms for multiple drug resistance in leukemia cells.
蛋白酶体抑制剂可选择性地促进肿瘤细胞凋亡，逆转多药耐药。
Proteasome inhibitors can selectively promote the apoptosis of tumor cells and overcome MDR.
此文就近年来有关胃癌多药耐药相关基因产物的临床研究作一综述。
This article is a review about the clinical investigation of MDR in gastric cancer, including multidrug resistance related gene products and detection.
目的探讨锌带基因ZNRD1在多药耐药胃癌细胞中的表达和作用。
Objective To study the expression and function of zinc ribbon gene ZNRD1 in drug resistant cells of gastric cancer.
目的探讨细菌感染及多药耐药对糖尿病足部溃疡疗效及预后的影响。
Objective To inquire into the influence of multidrug-resistant bacteria infection on diabetic foot.
因此，进一步了解非经典的耐药途径对于完善多药耐药机制有重要意义。
Hence, it is very important to further study the non-classical mechanism of multidrug resistance.
前言：观察三物白散加味方对肿瘤多药耐药(MDR)基因表达的影响。
To observe the effect of Modified "Sanwubai Powder" in affecting Multidrug resistance (MDR) gene expression of tumor.
目的：观察三物白散加味方对肿瘤多药耐药(MDR)基因表达的影响。
Objective To observe the effect of Modified Sanwubai Powder in affecting Multidrug resistance (MDR) gene expression of Tumor.
目的研究多药耐药(MDR- 1)基因在急性白血病(AL)治疗中的表达。
Objective To study on the expression of multiple drug resistance (MDR 1) gene during treatment course of acute leukemia (AL).
肿瘤多药耐药的机制十分广泛，其中以ATP结合盒式结构超家族成员研究较多。
The mechanism of multidrug resistance is vary, while much attention was paid on the expression of ABC(ATP binding cassette) transporter.
目前的研究发现，有多类细胞色素P 450酶与肿瘤多药耐药的发生密切相关。
In recent years, researches found that there were many kinds of cytochrome P450 enzymes which related to multidrug resistance of tumor.
文章重点综述目前研究较多的多药耐药机制，并对肿瘤耐药逆转进展作简要介绍。
This paper provides a review on the hotspots of current MDR research. Moreover, the recent progress in the field of MDR reversal is also briefly introduced.
目的探讨人乳腺癌细胞化疗敏感性与多药耐药相关基因和凋亡调控基因表达的关系。
Objective To explore the relationship of chemotherapy sensitivity and expression of multidrug resistance genes and apoptosis regulation genes in human breast cancer cell lines.
结论P -糖蛋白介导的多药耐药是膀胱癌腔内灌注化疗失败、肿瘤复发的重要原因。
Conclusion the P-glycoprotein-mediated MDR may be an important cause of recurrent of bladder cancer after treated by perfusion chemotherapy.
目的探讨食管癌患者肿瘤组织中多药耐药(MDR)基因表达及其在临床上的应用价值。
Objective To explore multidrug resistance (MDR) gene expression in tumor tissue of esophageal carcinoma and its application value in clinical.
背景与目的：多药耐药在膀胱癌化疗失败中起着重要作用，关于其机制还不是十分清楚。
BACKGROUND & OBJECTIVE: Multidrug resistance plays an important role in chemotherapy failure of bladder cancer, but its mechanism is unclear.
目的分析对碳青霉烯耐药或不耐药的铜绿假单胞菌的多药耐药情况，并探讨其相关因素。
Objective To study the multi-drug resistance of Pseudomonas aeruginosa resistant or sensitive to carbapenem and to analyze correlated factors.
目的探讨人肺癌细胞株对化疗药物的敏感性与多药耐药相关基因和凋亡调控基因表达的关系。
Objective To explore the relationship of chemotherapy sensitivity and expression of multidrug resistance genes and apoptosis regulation genes in human lung cancer cell lines.
目的：研究粉防己碱与长春新碱合用能否逆转人乳腺癌M CF 7多药耐药细胞的抗凋亡作用。
Objective: to study whether the anti-apoptotic action is reversed by tetrandrine in a combination with vincristine in human breast carcinoma MCF-7 multidrug-resistant cells.
目的：研究粉防己碱与长春新碱合用能否逆转人乳腺癌M CF 7多药耐药细胞的抗凋亡作用。
Objective: to study whether the anti-apoptotic action is reversed by tetrandrine in a combination with vincristine in human breast carcinoma MCF-7 multidrug-resistant cells.
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