在发现人类胚胎干细胞的十年之后,科学家们仍致力于研究将多能细胞“哄骗”成为成熟组织细胞的标准过程。
Ten years after the discovery of human es cells, scientists are still working on standardizing procedures for coaxing pluripotent cells to become mature tissue.
胚胎干细胞也有多能性,通过一种被称为诱导多能性的方法而被基因重组的细胞同样具有多能性。
Embryonic stem cells are also pluripotent, as are cells that have been genetically reprogrammed through a process called induced pluripotency.
然而令Loring惊喜的是,相应的人类基因确实能把这两种动物的细胞转换成称为诱导多能干细胞(iPS细胞)的类胚胎干细胞。
To Loring's surprise, however, the corresponding human genes did transform both animals' cells into embryonic-like stem cells called induced pluripotent stem cells (iPS cells).
而每一位从事“诱导多能性”细胞研究的科学家都坚持认为,源自体外受精疗法多余胚胎的传统胚胎干细胞研究,必须继续。
However every scientist working on ips cells insists research on conventional embryonic stem cells derived from surplus embryos after in vitro fertilisation treatment must continue.
我感觉这些细胞像人胚胎干细胞一样是多能的。
I feel these cells are pluripotent like human embryonic stem cells.
已有一些证据证实诱导多能干细胞在基因表达方面,并不与胚胎干细胞完全相同,它仍保留有其来源组织的一些细胞记忆。
And there is some evidence that iPS cells aren't exactly like embryonic stem cells in their gene expression, retaining a subtle cellular memory of the tissue they came from.
在这一过程中的目的基因是一个可以编码OCT4转录因子,让胚胎干细胞维持多能性。
The targeted gene in the process is one that codes for the Oct4 transcription factor, which allows embryonic stem cells to remain pluripotent.
科学家已经把来自猪的细胞诱导转变成了多能干细胞——这种细胞就像胚胎干细胞一样,有能力发育成身体中的任何类型的细胞。
Scientists have managed to induce cells from pigs to transform into pluripotent stem cells - cells that, like embryonic stem cells, are capable of developing into any type of cell in the body.
多能性人类胚胎干细胞是从胚胎衍生而来的细胞,具有发育成上百种细胞的可能。
Biologically, so-called pluripotent human embryonic stem cells have not made up their minds about what to become.
本文主要综述胚胎干细胞、骨髓间充质干细胞、多能性诱导干细胞的定向分化在新药研发中的作用及研究进展。
This paper reviewed the progress of new drug research of the directed differentiation of embryonic stem cells, bone marrow mesenchymal stem cells and induced pluripotent cells.
脂肪干细胞是已知的多能干细胞,它们能产生多种细胞、组织类型,但是他们不如胚胎干细胞全能性。
The stem cells found in fat are known as multipotent stem cells. They can produce a variety of cell and tissue types, but are not as flexible as embryonic stem cells.
主要研究者认为,该试验将改进临床方法,成为用多能干细胞或胚胎干细胞分化而来的细胞进行治疗的跳板。
The trial will refine clinical methods and be a "steppingstone" to therapies with cells derived from iPS or hES cells, says the principal investigator.
这些发现说明,相对于胚胎干细胞的后代,从诱导多能干细胞分化来的某些细胞中异常的基因表达会在同基因的受体身上引起T细胞依赖的免疫反应。
These findings indicate that, in contrast to derivatives of ESCs, abnormal gene expression in some cells differentiated from iPSCs can induce T-cell-dependent immune response in syngeneic recipients.
这些发现说明,相对于胚胎干细胞的后代,从诱导多能干细胞分化来的某些细胞中异常的基因表达会在同基因的受体身上引起T细胞依赖的免疫反应。
These findings indicate that, in contrast to derivatives of ESCs, abnormal gene expression in some cells differentiated from iPSCs can induce T-cell-dependent immune response in syngeneic recipients.
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