本系列的第2部分进一步讨论构造数据模型方面的最佳实践，包括利用Hibernate的多态性、泛型DAO的其他有用特性以及数据模型的性能调优。
Part 2 of this series covers more best practices in constructing a data model by leveraging polymorphism with Hibernate, other useful features of a generic DAO, and performance tuning the data model.
基因多态性研究可为预防adr提供新的参考依据，临床可在药物治疗前对患者进行基因型检测，以降低adr的发生率。
Gene polymorphism study can provide a new reference for the prevention of ADR. Gene detection can be conducted before drug treatment to reduce the incidence of ADR.
因每个SSR序列的基本单元重复次数在不同基因型间差异很大，从而形成其座位的多态性。
The repeat times of basic units of each SSR sequence are different among different genotypes, so polymorphism of the seat is formed.
本研究也证明了RAPD和SSR两种分子标记在检测不同的AA组型水稻品种间多态性方面是很有效的方法。
It is also demonstrated from this study that both RAPD and SSR analyses are powerful methods for detecting polymorphisms among the different AA genome Oryza accessions.
目的探讨大多功能蛋白酶（LMP）2基因多态性与胰岛素依赖型糖尿病（IDDM）及DR3基因的关系。
Objective To investigate the relationship of polymorphism of large multifunctional protease (LMP) 2 genes to insulin dependent diabetes mellitus (IDDM) and DR3 gene.
目的：探讨南京地区汉族人群中对氧磷酶1基因（PON1）多态性与2型糖尿病是否存在相关性。
Objective: To explore the relationship between microsatellite DNA polymorphism of human PON1 gene and type 2 diabetes mellitus in Chinese population of Nanjing.
本研究采用淀粉凝胶电泳法对我国长江流域五个沼泽型类群的395头水牛型清白蛋白多态性进行了检测。
The serum albumin polymorphism of 395 animals from five swamp buffalo types in the Changjiang River valley were analyzed by starch gel electrophoresis.
目的研究中国汉族人群abo基因多态性，并将基因分型技术用于解决临床输注中血型血清学难题。
Objective to study ABO gene polymorphism of Chinese Han population and apply ABO genotyping technology to solve the serological problems of clinical transfusion.
目的建立变形菌随机扩增dna多态性分型技术，应用于临床菌株流行病学调查。
OBJECTIVE To establish the random amplification of polymorphic DNA (RAPD) typing technology for Proteus strains and apply it in the epidemiology investigation.
方法采用聚合酶链反应-限制性片段长度多态性分析(PCR - RFLP)检测136例HBVDNA阳性的上海籍HBV感染者的基因型。
Methods HBV genotypes were detected by polymerase chain reaction (PCR) and restriction fragment length polymorphism analysis (RFLP) in 136 HBV DNA positive patients who were born in Shanghai.
方法：采用RAPD技术对不同产地的商品药材前胡进行多态性分析，并构建聚类树型图。
Methods: Analyzing polymorphics of commercial medicinal materials "Qian-Hu" at different regions by RAPD technique and constructing a clustering tree diagram.
分析er基因多态性与骨密度关系以及各基因型在骨质疏松组与对照组的分布。
The relationship between er genotype and BMD, the distribution of er genotype between case group and control group were evaluated.
目的研究载脂蛋白E基因多态性与脑梗死的关系及不同等位基因型血脂水平的特点。
Objective To study the relationship between gene polymorphism of apolipoprotein E and cerebral infarction(CI) and the characteristics of the serum lipid level with different genotypes.
方法建立随机扩增多态性DNA聚丙酰胺凝胶电泳（RAPD-PAGE）指纹分型法；
Methods To establish a fingerprinting method by random amplified polymorphic DNA and polyacrylamide gel electrophoresis (RAPD-PAGE).
采用脉冲场凝胶电泳（PFGE）和随机引物多态性DNA（RAPD）分型对128株CRAB进行分子流行病学研究；
The homology of 128 isolates of CRAB was determined by both pulsed field gel electrophoresis (PFGE) and randomly amplified polymorphism DNA (RAPD).
目的：探讨ace基因多态性与2型糖尿病心血管并发症之间的相关性。
OBJECTIVE: To investigate the correlation between the polymorphism of ACE gene and the cardiovascular complications of type 2 diabetes.
结论单纯型肥胖儿童瘦素受体基因第20外显子存在基因多态性的变化，且这种变化明显影响肥胖儿童的脂质代谢及体脂分布。
Conclusion There is polymorphism at 20 exon LEPR gene in children with obesity, which may affect the lipid metabolism and the fat distribution.
方法采用RAPD技术对商品药材百合进行了多态性分析，并构建聚类树型图。
Methods Polymorphic analysis was used for the commercial crude drug Bulbus Lilii with RAPD technique and a tree diagram was constructed.
目的从分子遗传水平进行基因多态性研究，以探讨2型糖尿病易伴发冠心病的内在原因。
Objective To explore the association of type 2 diabetes with coronary heart disease (CHD), from gene polymorphism analysis.
为探讨2型糖尿病和非糖尿病群体间的遗传多态性差异，寻找2型糖尿病的致病相关基因。
To explore the genetic polymorphic difference between Type 2 diabetes and non diabetes controls, and to find out the related disease genes of Type 2 diabetes.
目的：探讨编码人磷酸核糖焦磷酸合成酶亚单位2的基因PRPS2单核苷酸多态性与产生过剩型痛风患者的关系。
Objective:This study inquired into the relation between single nucleotide polymorphisms (SNP) of PRPS2 gene and overproducing type of gouty patients.
目的：探讨混合型高脂血症与肝脂酶基因启动子250G/A多态性的关系。
Objective To study the interaction between hepatic lipase gene-250G/A polymorphism and combined hyperlipidemia.
结论ICAM- 1 K469E多态性与2型糖尿病伴发肾病的发生有关，K等位基因可能是DN的易感基因。
Conclusions K469E polymorphism of ICAM-1 is associated with type 2 DN, and K allele may be susceptible to DN.
目的调查y染色体7个STR位点及单倍型的遗传多态性并分析其群体差别。
Objective To investigate the genetic polymorphism of7Y-STR loci and haplotypes and analyze their population difference.
目的：寻找丙戊酸药物浓度与CYP2C19基因多态性的关系，以便临床根据患者的基因型进行个体化给药。
OBJECTIVE To investigate the association between valproic acid (VAP) plasma concentration at steady state (Css) and CYP2C19 gene polymorphisms for better individualized medication.
结论中国原发性高血压人群中，AT 1 R基因A 1166c多态性aa基因型可能与血压升高有关；可能与中国人群原发性高血压左心室肥厚无关。
Conclusion in Chinese essential hypertension population, AA genotype of A1166C polymorphism of AT1R gene is possibly correlated with increased blood pressure but not with left ventricular hypertrophy.
方法对110名重庆汉族个体，采用降落式PCR和限制性片段长度多态性法（RFLP）进行基因型分析。
Methods Single round Touchdown PCR (TD PCR) and restriction fragment length polymorphism (RFLP) method were used for genotyping in 110 people from the Han population in Chongqing.
目的应用随机扩增DNA多态性（RAPD）技术对医院感染的粘质沙雷菌进行基因分型。
Objective To evaluate the genetic polymorphism of Serratia marcescens by randomly amplified polymorphic DNA (RAPD) method.
方法在140名汉族健康人的外周血中，应用聚合酶链反应（PCR）限制性片段长度多态性分析（RFLP）及多重PCR技术，进行NAT1等位基因分型研究。
Methods Using multiple PCR and PCR-RFLP methods, we studied the NAT1 genotypes and its genetic polymorphisms of the peripheral blood samples from 140 Han people.
方法：综述近几年具遗传多态性代谢酶的探针药物、代谢分型方法以及影响因素。
METHOD:The probe drugs of drug metabolism, methods of phenotype and related factors were reviewed.
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