目的比较正常大鼠消化道不同部位多巴胺能细胞的分布性差异。
Objective To study the different expression of dopaminergic cells in different parts of rat gastrointestinal tract.
结论本次实验结果提示多巴胺对多巴胺能细胞的毒性是通过氧化应激途径起作用的。
Conclusions Our results suggest that the oxidative stress plays a crucial role in the toxic effect of dopamine on dopaminergic cell.
结论:蛋白酶体抑制剂mg132能够抑制多巴胺能细胞PC 12的增殖并诱导细胞凋亡,蛋白酶体活性的丧失可能影响到多巴胺能细胞的生存。
CONCLUSION: MG132 can inhibit the proliferation of dopaminergic PC12 cells and lead to apoptosis. The disfunction of proteasome may do harm to the existence of dopaminergic cells.
目的探讨磺酰罗丹明B法检测多巴胺能神经细胞的最佳条件。
Objective To explore the optimal detecting conditions of the dopaminergic neural cell by SRB assay.
目的从胚胎大鼠脊髓神经管中分离神经上皮干细胞并诱导其向多巴胺能神经元方向分化。
Objective to isolate neuroepithelial stem cells from the spinal cord neural tube of the embryonic rat and induce them to differentiate into dopaminergic neurons.
目的探讨纹状体组织对胚胎干细胞向多巴胺能神经元分化的定向诱导作用,及其细胞来源和诱导方式。
Objective To explore the inductive effect of striatal tissue on mouse embryonic stem cells and further analyse the cell source and inductive pattern of this inductive effect.
目的寻求无血清、无饲养层细胞存在的情况下,胚胎干细胞向多巴胺能神经元定向诱导分化的最佳条件。
Objective to explore the optimal condition of direct differentiation into dopaminergic neurons of embryonic stem cells in serum-free and feeder layer cell free medium.
目的:建立一种简单高效的中脑多巴胺神经元细胞原代培养方法,并观察胰酶消化对中脑多巴胺能神经元突起生长的损伤作用。
Objective: To establish an easy and high-yield method of rat dopaminergic neuron primary culture, and to observe the damage to the neurites by the trypsogen.
目的:观察不同浓度抗坏血酸对神经干细胞向多巴胺能神经元分化的影响。
OBJECTIVE: to investigate the effects of ascorbic acid on the differentiation of neural stem cells into DA neurons in vitro.
结论:胚胎神经上皮细胞多数为神经干细胞,黑质内移植后可以存活并分化为多巴胺能神经元。
Conclusion: Present findings demonstrate that embryonic neural stem cells dissociated from neural tube can survive and differentiate into dopamine neurons.
而HNG - E则为发生转化的神经干细胞系,但能在RA诱导下向多巴胺能神经元分化。
HNG-E cells were characterized as transformed neural stem cells, and can be differentiated into dopaminergic neurons by ra induction.
结论GDNF能促进PD模型大鼠黑质内神经元前体细胞向多巴胺能神经元方向分化。
Conclusion GDNF might be able to promote the neuronal precursors in the SN of PD rats to differentiate into DA neurons.
结论移植的神经干细胞能在PD模型小鼠纹状体存活,并可分化出特定的多巴胺能神经元。
ConclusionsThe transplanted multipotent NSCs could survive, differentiate into functional dopamine neurons in the brains of PD model mice.
结果(1)基因工程细胞可防止多巴胺能神经元退变死亡,与对照组比较,最多增加了95 4 %,P。
Results The number of dopaminergic neurons protected by engineered cells increased at least by 95.4% in comparison with the control cells (P<0.01).
目的动态研究多巴胺对多巴胺能神经细胞的细胞毒作用。
Objective to study the cytotoxicity of dopamine to dopaminergic SH-SY5Y neuroblastoma cells in a dynamic style.
目的动态研究多巴胺对多巴胺能神经细胞的细胞毒作用。
Objective to study the cytotoxicity of dopamine to dopaminergic SH-SY5Y neuroblastoma cells in a dynamic style.
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