检测诱导痰中的炎症指标并不能反映外周气道功能的改变。
The inflammation profile detected by induced sputum did not reflect the dysfunction of peripheral airways.
结论COPD急性加重期较稳定期肺功能显著下降，肺过度充气和外周气道阻力增加是急性加重期肺功能恶化的主要原因。
Conclusions Pulmonary function of COPD decreased significantly from stable stage to exacerbation, the main reasons of which were hyperinflation and the increasing of peripheral airway resistance.
结论COPD急性加重期较稳定期肺功能显著下降，肺过度充气和外周气道阻力增加是急性加重期肺功能恶化的主要原因。
Conclusions Pulmonary function of COPD decreased significantly from stable stage to exacerbation, the main reasons of which were hyperinflation and the increasing of peripheral airway resistance.
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