前言: 目的:合成塞曲司特并对其合成工艺进行改进。
OBJECTIVE: To Synthesize seratrodast and improve the synthetic process.
方法:以庚二酸单乙酯为原料,经酰氯化、傅克酰化、还原、水解、缩合及氧化反应合成塞曲司特。结果:塞曲司特的总产率为5 0 .7%。
Methods and results:Through acylation, Friedel Crafts reaction, reduction, hydrolysis, condensation and oxidation, the title compound was prepared with a total yield of 50.7%.
方法:以庚二酸单乙酯为原料,经酰氯化、傅克酰化、还原、水解、缩合及氧化反应合成塞曲司特。结果:塞曲司特的总产率为5 0 .7%。
Methods and results:Through acylation, Friedel Crafts reaction, reduction, hydrolysis, condensation and oxidation, the title compound was prepared with a total yield of 50.7%.
应用推荐