这是因为一旦知道药效基因，药物化学家就可以修饰它，在保持药效的基础上减少毒性。
This is because once a pharmacophore is known, medicinal chemists can modify it to reduce toxicity while maintaining (or enhancing) potency.
病理基础是预处理毒性引起肝脏内肝小叶3区内的血窦内皮细胞以及肝细胞损害所致。
The basis of pathology of vod is thought resulting from injury of hepatocytes and endodermis cells surrounding the central veins in zone3of the liver acinus by regimen-related toxicity.
结论目前黄药子针对功效、物质基础和毒性的研究都是孤立的，彼此之间缺少关联性。
Conclusion Recent studies on its function, material base and toxicity were isolated that lack of relative study.
对安克素胶囊的制备工艺、质量标准、动物急性毒性及抗癌活性等进行了系统研究，为临床应用奠定了基础。
Systematic studies on preparation technology, quality standard, acute toxicity and antineoplastic activities were performed. The results established bases for its clinical use.
在广泛检索文献的基础上，对龙葵素的资源、药理、毒性及药用等方面的研究成果进行了概述。
On the basis of searching in a wide range of literature, the research results were summarized from the aspects such as the resources, pharmacology, toxicity and medicine use of solanen.
目的：研究草棉花瓣提取物总黄酮(FGF)的毒性、抗炎免疫等方面的药效学，为研究和开发新疆的地方药用植物奠定基础。
Objective: to study the toxicity, anti-inflammatory and immune enhancing properties of Flos Gossipium Flavonoid (FGF) in Xinjiang and contribute to full exploitation of medicinal herbs in Xinjiang.
目的建立一个简便易行的动物模型及细胞毒性T细胞(CTL)检测体系，为HCV感染中ctl作用研究奠定理论基础。
Objective to establish a simple animal model and the cytotoxic t cell (CTL) detecting system for the studies of the effects of CTL on HCV infection.
目的对纳米锶磷灰石进行体外细胞毒性试验，评价其生物安全性，为将其应用于骨折临床修复奠定基础。
Objective Nano- fermorite was tested by in vitro cytotoxicity as first step for future use of this material as orthopedic implant.
目的探讨庆大霉素诱发的中毒性急性肾小管坏死动物模型的建立，研究其在基础及临床科研中的价值。
Objective to discuss the foundation of the animal model of gentamicin-induced toxic acute tubular necrosis and approach its value scientific research.
在此基础上，初步探讨苯酚类化合物的毒性机制。
On this basis, an initial inquiry is made into the mechanism of toxicity of phenol chemicals.
减少火灾烟气毒性危害最基础的工作离不开材料产烟毒性评价，然而试验方法的标准化工作进展缓慢。
The assessment of the fire effluent of the materials is the basic research item to reduce the toxicity to human beings, however, the standardization of the test method has got a very slow progress.
文章在分析大量病毒性营销案例的基础上，对病毒性营销的载体、网络上实现的途径及其误区进行了研究。
This paper illustrates the carrier, the operating approaches on the Internet and the risk of the viral marketing based on the analyses on the viral marketing cases.
目的在本实验室建立小鼠胚胎成纤维细胞培养方法，并在此基础上用培养的细胞检测氯化镉、甲醛等外来化合物的细胞毒性反应。
Objectives: To set up the methods of mouse embryo fibroblasts culture in vitro and to evaluate the toxicity of xenobiotics such as chloride cadmium and formaldehyde by using these methods.
本文在前人的基础上研究了不同卷烟主流烟气的细胞毒性及致突变性，现总结实验结果如下：1。
On the basis of former studies, this paper studies on cytotoxicity and mutagenicity of different mainstream cigarette smoke, the main experimental results are as follows: 1.
方法：采用大肠杆菌内毒素复制大鼠内毒性热瘀证模型基础上，检测桃核承气汤对血液流变学和凝血指标的影响。
Method: Take Bacillus Coli endotoxin to copy rats endotoxic heat - stasis syndrome model, then test the effect of PRC on rheology and coagulation indexes.
因而在化疗的基础上配合中医药治疗将起到良好的增效和减轻毒性等多方面的作用。
Therefore, traditional Chinese medicine therapy will bring multifaceted effects like efficacy enhancing and toxicity reducing when combined with chemotherapy.
21世纪初，许多营销策略和工具都是基于以互联网为基础，病毒性网络营销是其中重要的一种。
At the beginning of 21st century, a lot of marketing strategies and tools are based on Internet, and viral network marketing is an important one among them.
在萘急性毒性试验基础上，通过亚致死毒性、致畸性和组织病理学等指标评价了萘的水生毒性。
On the base of acute toxicity test on naphthalene, we've assessed the aquatic toxicity of naphthalene by sub-lethal toxicity and teratogenicity.
这些结果揭示出了这种细菌毒性机制和相关的基础细胞信号过程。
The results may shed light both on how the bacterium kills and on fundamental cell signaling processes.
本文以近年来该领域的研究成果为基础，综述了有机磷农药对海洋动物乙酰胆碱酯酶的毒性效应。
Based on the previous reports in this field, the toxicity of organophosphorus pesticides to AChE in Marine animals is reviewed in this paper.
本文以近年来该领域的研究成果为基础，综述了有机磷农药对海洋动物乙酰胆碱酯酶的毒性效应。
Based on the previous reports in this field, the toxicity of organophosphorus pesticides to AChE in Marine animals is reviewed in this paper.
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