目的介绍在遗传流行病学病例对照研究中，应用多因子降维法（MDR）分析基因-基因交互作用。
Objective To introduce the application of Multifactor Dimensionality Reduction (MDR) method for detecting gene-gene interactions in genetic case-control studies.
数年前，他提炼出一种技术，可以将基因网络“毛团”——对基因交互作用密集纠结的描绘——转化成分层图。
Several years ago, he refined a technique for turning gene-network "hairballs" - densely tangled depictions of gene interaction - into hierarchical maps.
对于基因数据，则采用回归树分析基因与基因之间、基因与环境之间的交互作用。
For analysis of genomic data, regression tree approaches to the analysis of interactions between genes and between genes and the environment will be used.
方法用PCR-RFLP技术分析了原发性肺癌组和住院对照组（各163例）的CYP1A1、GSTM1基因的多态性、基因型分布频率和交互作用。
Methods CYP1A1 and GSTM1 genetic polymorphisms were determined by PCR-RFLP in 163 lung cancer cases and healthy controls respectively.
毒理基因组学主要在基因组水平上研究机体对环境因子的应答反应，了解基因和环境交互作用在疾病发生中的作用。
Toxicogenomics mainly study the response of human body to the environmental elements, and understand the effect of gene-environment interaction to the disease in molecular level.
毒理基因组学主要在基因组水平上研究机体对环境因子的应答反应，了解基因和环境交互作用在疾病发生中的作用。
Toxicogenomics mainly study the response of human body to the environmental elements, and understand the effect of gene-environment interaction to the disease in molecular level.
应用推荐