像老年痴呆症这样的疾病会影响NR2B的表达,而可以使该基因过表达的药物能够抵消这些疾病的影响。
Diseases like Alzheimer's affect NR2B expression, so a drug that causes the gene to over-express could counteract the affects of the disease.
这只转基因鼠小弟名叫荷比-杰。通过使控制其神经元传输的基因过表达,它走迷宫和记忆玩具的能力得到了极大的提升。
The genetically engineered rat, Hobbie-J, over-expresses a gene that regulates neuron communication, greatly enhancing the rat's ability to navigate mazes and remember toys.
基因无效或过表达的生理学模型将成为珍贵的检测这些生物新发现的工具。
Physiological models with invalidated or over-expressed genes will be precious tools to check these new biological discoveries.
这是因为很多细胞运动的研究使用遗传改造来抑制或增强基因表达。这些改造过的基因被认为参与了这个过程。
That is because a lot of research on cell movement USES genetic modification to silence or amplify genes thought to be involved in the process.
不是所有猴子都像患有该综合症的人类一样,带有两组MECP2基因,但是大多数猴子的MECP2基因比正常的猴子要多,这是基因的过表达。
The monkeys did not all have two copies of MECP2, as in the human syndrome, but most had more MECP2 than normal, an overexpression of the gene.
转录靶向性利用一些肿瘤过表达某些特定基因,所以使用此基因特异性启动子可以驱动治疗基因达到靶向性治疗目的。
Transcriptional targeting takes advantage of the fact that some cancer cells express a subset of exclusive genes, and USES these cancer-specific promoters to express the desired transgenes.
它在鼻咽癌细胞和组织中表达明显下调,过表达BRD7基因可抑制鼻咽癌细胞的生长和细胞周期的进程。
It is obviously down-regulated in nasopharyngeal carcinoma (NPC) cells and tissues. Over expression of BRD7 in NPC cells can inhibit cell proliferation and cell cycle progression.
同样,在公开的乳腺癌基因表达数据库中,SF3B 3过表达与总生存率显著相关,SF 3b1则无此作用。
Similarly, in publicly available breast cancer gene expression data sets, overexpression of SF3B3, but not SF3B1, was significantly correlated with overall survival.
表达阵列分析显示过表达CT120B诱导的基因表达谱变化;
The differential gene expression induced by overexpressed CT120B was investigated using Atlas cDNA expression array.
目的:探讨过表达NDRG1基因对HT-29人结肠癌细胞株体外增殖、侵袭能力的影响,分析NDRG1与大肠肿瘤增殖、侵袭的关系。
Purpose:To investigate the effects of NDRG1 on proliferation and invasiveness of human colorectal cancer cell line HT-29 in vitro.
此外,生长素处理去顶植株影响了细胞分裂素合成基因的表达,表明D10通过降低生长素的水平促进细胞分裂素的合成。
Furthermore, effects of auxin treatment of decapitated plants on the expression of cytokinin biosynthetic genes suggest that D10 promotes cytokinin biosynthesis by reducing auxin levels.
研究发现自闭症患者大脑中的炎性细胞因子、趋化因子及生长因子是过表达的。而且自闭症患者的免疫基因表达和干扰信号通路也存在极大的差异。
Cytokines, Chemokines, and Growth Factors in ASD brain are found elevated, and the immune gene expression and the Interferon signaling pathway are found significantly different in the ASD.
方法:用脂质体转染携带PTTG基因的表达质粒,构建过表达PTTG基因的垂体细胞株,观察细胞形态。
Methods: Transfect plasmid which carries PTTG gene use liposome, constructs the pituitary cell line which high express PTTG gene, observe the cell form.
HBP1通过抑制促细胞增殖基因mif的表达抑制肿瘤细胞生长。
HBP1 inhibition of cancer cells growth is achieved at least partially by suppressing MIF expression.
结论:(1)在正常垂体细胞中过表达PTTG基因也可以引起细胞癌变,增强侵袭能力。
Conclusion: (1) High expressed the PTTG gene in the normal pituitary gland cell also to be possible to cause the cell cancer, enhancement attack ability.
CDK9基因的过表达未引起细胞周期发生显著变化,其可能并不参与细胞周期的调控。
Its overexpression did not cause significant changes in cell cycle, which seemed that no detectable relationship existed between CDK9 and cell cycle regulation.
因此,我们检测了左心室收缩功能障碍并继发肿瘤坏死因子(TNF1.6)过表达的转基因老鼠腺苷水平和选择性ar的表达。
Therefore, we assessed adenosine levels and selective ar expression in transgenic mice with left ventricular systolic dysfunction secondary to overexpression of tumor necrosis factor - (TNF 1.6).
因此,我们检测了左心室收缩功能障碍并继发肿瘤坏死因子(TNF1.6)过表达的转基因老鼠腺苷水平和选择性ar的表达。
Therefore, we assessed adenosine levels and selective ar expression in transgenic mice with left ventricular systolic dysfunction secondary to overexpression of tumor necrosis factor - (TNF 1.6).
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