结论PLGA纳米粒子可作为基因载体。
结果对囊泡作为药物和基因载体的研究具有启发意义。
The results can benefit the fabrication of vesicles as encapsulation vectors for drug and gene delivery.
其二，研究了基因载体的结构对于基因转染效率的影响。
In the second part, we investigated the influence of gene delivery vectors on gene transfection efficiency.
建立了一种基于二氧化硅微颗粒的基因载体的制备新方法。
A new method for the preparation of gene carriers based on silica micro-particles was reported.
结论药物或基因载体的研究较多，但是尚未找到一种理想的载体材料。
Conclusions Drug or gene carries is a hot subject, but there is still no perfect carries.
本文将概述无机纳米粒子作为基因载体的现状及其对基因表达的影响。
This paper reviewed the current researches about inorganic nanoparticles as gene delivery vectors. Their influence on the gene expression was also discussed.
基因载体是将治疗基因导入肿瘤细胞的载体，在基因治疗中起关键的作用。
The vectors employed for glioma gene therapy are widely developed and used in clinical trials.
结果构建并鉴定了系列截短的NOS1 启动子萤光素酶报告基因载体；
Results A series of truncated NOS1 promoter luciferase reporter vectors were constructed and identified.
含气体微泡既可以作为医学超声显像的造影剂，又可以作为药物或基因载体。
As ultrasound contrast agents for medical ultrasound imaging, gas-filled microbubbles can also be used as drugs or gene carriers.
本文从阳离子聚合物结构改造策略等方面综述了其作为基因载体的研究进展。
The latest advances on new cationic polymers as gene vectors home and abroad were reviewed in this paper.
目的制备基因载体壳聚糖纳米粒，研究其结构特征及其体外对细胞的转染活性。
Objective to prepare chitosan nanoparticles as gene vectors so as to investigate their structural characteristics and cell-gene transfection efficiency in vitro.
非病毒的基因载体比病毒性基因载体具有高安全性、低免疫原性及易于生产的特点。
Nonviral gene vectors have many inherent advantages over viral vectors in terms of safety , immunogenicity and ease of manufacture.
而载体的选择是基因治疗的关键，所以研究者们不遗余力的寻找安全、高效、稳定的基因载体。
But the genetic carrier is key point to gene therapy, consequently many researchers spare no effort to find more safe, high performance and stable genetic carrier.
聚氨基酸材料由于可生物降解性，低毒性等特点而被广泛的作为非病毒性基因载体材料的研究。
Polyaminoacid materials are widely researched as non-viral gene vectors because of the advantages, such as biodegradation, low cytotoxicity and so on.
非病毒基因载体主要有脂质体、人工合成聚合物载体、天然聚合物载体、局部基因释放载体等。
Nonviral gene carriers include liposomes, synthetic polymeric vectors, natural polymeric vectors, local gene delivery vectors and so on.
目的构建磷脂酰肌醇蛋白聚糖3 (GPC3)启动子荧光素酶报告基因载体，并验证其转录活性。
ObjectiveTo construct glypican-3 (GPC3) promoter luciferase reporter gene vector, and to analyze its transcriptional activity.
腺病毒载体是继逆转录病毒载体后在基因治疗、基因免疫等方面应用开发得较早且较成熟的一种基因载体。
Adenovirus vector is an earlier and maturer genetic carrier in the respect of gene therapy and genetic immunization after retroviral vector.
此外，由于具有多能性，间充质干细胞还是很好的基因载体，在创伤修复的基因治疗中有广阔的应用前景。
In addition, for its multi potential to differentiate into lineages of mesenchymal tissues, MSC could be used as gene vehicle for gene therapy of trauma care.
该启动子的成功克隆和其报告基因载体的构建，为研究SOD2的基因表达调控机制提供了重要基础和工具。
The reporter gene vector driven by SOD2 promoter will provide an experimental tool for the further study on the regulatory mechanism of the SOD2 expression.
壳聚糖作为基因载体的主要缺陷是转基因效率比较低，所以研究者们试图通过修饰以增加壳聚糖的转基因效率。
The major drawback of being a gene delivery vector is the low efficiency of transfection, so the scientists have been trying to increase the efficiency of chitosan with the methods of modifications.
结论树状聚合物的特殊结构决定了它的独特性质，树状聚合物在药物传递系统、基因载体等领域具有广阔的应用前景。
Conclusion the unique properties of dendrimers resulting from their unusual structure gave a broad application prospect in the drug delivery system, genetic carriers and other fields.
无机纳米颗粒类非病毒型基因载体因其稳定性好、生物亲和性好、安全、有效、无免疫原性等优点，已引起广泛关注。
Inorganic nanoparticles as non-viral gene carriers have caught much attention because of their good stability, biocompatibility, safety, efficiency and non-immunogenicity.
概括了囊泡在反应微环境、药物释放、基因载体和生物矿化等方面的潜在应用；并提出了聚合物构筑囊泡的发展前景。
The potential applications of the polymeric vesicles in some fields, such as micro-circumstance, the release of drug, gene engineering and biomineralization were introduced.
文章综述了载药纳米粒与血脑屏障的相互作用机制，以及纳米粒作为药物和基因载体用于中枢神经系统疾病治疗的研究进展。
The article reviews the interaction mechanism between drug-loaded nanoparticles and the BBB, as well as the recent advances in the treatment of CNS diseases with nanoparticles as a dru...
聚合物纳米体系在药物传递和基因载体方面具有重要的科研价值和广阔的应用前景，这方面的研究已成为当今生物医学材料界最活跃的领域之一。
Polymer nanoparticles are used as carriers for the delivery of drug and gene. It has been one of the most attractive areas because of its scientific value and potential of application.
从分子生物学和免疫学的角度介绍埃博拉病毒蛋白，着重介绍GP和VP 30蛋白的结构及其在病毒转录过程中的作用机制，并对其在基因载体上的应用作出展望。
In this paper, the structure of Ebola virus GP and VP30 and their functions in transcription are introduced. Its application on gene carrier is also discussed.
本研究旨在构建具有猪 MSTN 前肽基因定点突变的真核表达载体。
This research intended to construct a eukaryotic expression vector with a site-directed mutation of porcine MSTN propeptide gene.
本研究旨在构建具有猪 MSTN 前肽基因定点突变的真核表达载体。
This research intended to construct a eukaryotic expression vector with a site-directed mutation of porcine MSTN propeptide gene.
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