用FCM检测不同浓度紫杉醇素对基因转导细胞的作用。
The effect of Taxol at different concentrations on mdr1 gene transfer cells was determined by FCM.
目的:观察GM-CSF基因转导的肿瘤细胞免疫小鼠的抗肿瘤效果。
Objective:To evaluate the antitumor effect of GM-C SF gene transfered Tumor Vaccine.
目的:研究多聚赖氨酸包被的球囊导管作在体定向基因转导的可行性。
Objective . This study was undertaken to test the feasibility of local gene transfer in vivo using polylysine- coated balloon catheter.
目的探讨重组杆状病毒作为哺乳动物基因转导载体的可行性及其转导特点。
Objective to study the feasibility and the characteristics of recombinant baculovirus as mammalian gene transfer vector.
随着安全措施的增加,我们相信我们可以干预在疾病早期的患者的基因转导。
With that added measure of safety, we believe we can intervene with gene transfer in patients at earlier stages of the disease.
目的:探讨造血基质细胞对人外周血干细胞体外培养扩增及基因转导的促进作用。
Objective: to inquire into the promoting effect of hematopoietic stromal cells on the culture and ex vivo expansion and the gene transduction of human peripheral blood stem cells.
结论:基质细胞的支持有维持造血干细胞原始造血活性及促进基因转导的双重好处。
Conclusion: the support exercised by the stromal cells would be of dual benefit to maintaining the primitive hematopoietic activity of hematopoietic stem cells and promoting the gene transduction.
目的:探讨降钙素基因相关肽(CGRP)基因转导兔动脉内膜对其舒缩功能的影响。
AIM: to study the effect of calcitonin gene related peptide (CGRP) on contraction and relaxation of iliac artery transduced with CGRP gene by retrovirus vector.
目的探讨稳定、高效、低毒的基因转导载体系统在基础研究和临床应用中的重要意义。
Objective to investigate the stable, high effective and low toxicity gene transfer vectors' basics in research and clinical application.
目的:探讨慢病毒载体在白血病细胞中的基因转导效率,为白血病基因治疗提供关键依据。
Objective to investigate the gene transduction efficiency of lentiviral vector in leukemia cells to provide key basis for leukemia gene therapy.
目的:探讨慢病毒载体在白血病细胞中的基因转导效率,为白血病基因治疗提供关键依据。
Abstract: Objective to investigate the gene transduction efficiency of lentiviral vector in leukemia cells to provide key basis for leukemia gene therapy.
近年来随着涎腺基因转导及组织工程等新技术方法的应用,涎腺功能重建取得了可喜的进展。
With the development of new technologies including gene transfer and tissue engineering, it is possible to reconstruct salivary gland functions.
结论:基于慢病毒载体基因转导的高效性,该载体系统可作为白血病细胞基因转导的极好工具。
Conclusion This lentiviral vector is an excellent gene transduction system for leukemia cells because of its high gene transduction efficiency.
基因疗法曾经由于缺少安全和有效的方法将治疗性基因转导入细胞内部而被认为没什么发展前景。
The promise of gene therapy has long been held up by the lack of a safe and effective way to insert the desired therapeutic genes into the right cells.
目的探讨白细胞介素-18 (IL - 18)基因转导对肺癌细胞系PG细胞肿瘤原性的影响。
Objective To investigate the effect of interleukin 18 (IL 18) gene transfer on the tumorigenesis of lung carcinoma cell line PG.
方法采用文献回顾的方法并结合当前实验研究,对肝细胞基因转导载体系统的研究和应用进展加以综述。
Methods Current status of hepatocyte directed gene transfer vectors were reviewed by history document and contemporary experimental advances analysis.
提示肿瘤细胞膜抗原及糖蛋白表达的改变可能是细胞因子基因转导影响肿瘤细胞免疫原性的重要结构基础。
The effect of various gene transduction on the expression of tumor cell MHC antigen and lectin receptors was investigated b…
细胞大规模培养、体细胞融合、基因转导等技术的研究和应用,可望从根本上改变甘薯传统的生产和育种模式。
The application of the techniques of large_scale cell culture, somatic cell fusion and gene transformation will greatly change the traditional mode of production and breeding of sweet potato.
通过建立荷人胃癌的裸鼠动物模型,分析基因转导后动物肿瘤细胞中内皮抑素的表达情况及对肿瘤的抑制作用。
Animal model of gastric cancer bearing nude mice were established to assay the expression of mouse endostatin and inhibition for tumor cell in vivo.
然而,肿瘤基因治疗同样面临一个特殊问题即转基因特异性表达于肿瘤部位问题,靶向性基因转导依然是目前基因治疗的一大障碍。
However, gene therapy for cancer is also faced with a specificity problem: the specific targeting of transgene expression to the site of the tumour.
结论:在RMA肿瘤模型中,GM -CSF基因转导的肿瘤细胞瘤苗有较好的抗肿瘤免疫效果,此法有可能成为治疗肿瘤的有效途径。
Conclusion: GM-CSF gene transfered tumor vaccine in RMA tumor model induced better antitumor immune effect and will be a novel approach to ca ncer in the future.
结果表明:在双基因逆转录病毒载体介导的小鼠骨髓细胞的基因转导中,IRES与内部SV40启动子相比,更能保证双基因的共同表达。
Results showed that IRES was superior to SV40 promoter for guarantee of genes co expression in bicistronic retrovirus mediated gene therapy.
如今,她们正试图弄清楚哪些分子信号转导过程激活了复苏植物的种子发育基因,以及如何将其复制到农作物上。
Now they are trying to figure out what molecular signaling processes activate those seed-building genes in resurrection plants—and how to reproduce them in crops.
如同其它癌症,卵巢癌细胞中的基因发生突变,结果产生了能够改变正常信号转导功能的蛋白。
Genes that are mutated in ovarian cancer, as in other cancers, result in the production of proteins that alter the normal function of signaling pathways in cells.
近年来的研究发现,许多癌基因和抑癌基因相关产物为细胞生长、增殖、分化等信号转导途径的成员。
It is known that many related products of oncogenes and anti - oncogenes take part in the signal transduction of grow, proliferation and differentiation of cells.
这样,通过转导CD 40 L基因有可能成为治疗恶性肿瘤的一种有效的方法。
Thus, gene transfer of CD40L has been proposed as an efficient means to treat malignancies.
该途径在高渗应激环境下控制信号转导和基因表达,是细胞生存所必需的。
In hyperosmotic stress, the HOG-MAPK pathway regulates the signal transduction and expression of numerous genes for cell survival.
但92.1%的株系表现为中抗或中感,表明转导目标基因可能仅起到部分提高抗性的作用。
The fact that 92.1% of lines were medium resistance or medium susceptible showed that target gene might only play partly role in sheath blight resistance.
结果转导CD基因可使MFC对5-FC高度敏感,并且显示出强大的“旁观者”效应。
Results MFC cells transduced with CD gene exhibited high sensitivity to 5 FC, especially showed the pronounced "bystander effects".
我们就能够查明转导蛋白质和基因,处于正确的位置。
We are now able to find proteins and genes that are at the correct location for the transduction machinery.
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