表型遗传学是一种可以从细胞传递到其子细胞的基因调控方式。
Epigenetics is a type of gene regulation that can be passed from a cell to its daughters.
通过遗传研究我们已经知道,基因调控方式的微小变更会在短时间内导致解剖学上的重大改变。
We now know from genetic studies that small alterations in the regulation of genes can have major anatomical consequences in a short amount of time.
2007年的试验结果令人眼界大开:染色体上藏着许多以前不为人知的位点,那里结合着各种各样的蛋白——可能是基因调控和表观遗传效应的温床。
The 2007 pilot results were eye-opening: Chromosomes harbored many previously unsuspected sites where various proteins bound—possible hotbeds of gene regulation or epigenetic effects.
外因遗传是一种可以传给下一代细胞的基因调控过程,最常见的方式是通过甲基化作用来完成,该作用可以让甲基(由一个碳原子和三个氢原子组成)附着于腺嘌呤或胞嘧啶上。
Epigenetics is a type of gene regulation that can be passed from a cell to its daughters. The most common mechanism is methylation.
这是基因调控是由控制基因的表观遗传完成的,并没有改变dna。
This gene regulation is accomplished by epigenetic processes that control gene expression without altering DNA.
基因转录是遗传信息传递和表达的枢纽,是基因表达调控机制发挥作用的重要环节。
Transcription is the first major step in gene expression, and constitutes an important point of genetic information flow.
在现代分子生物学技术研究中,常常需要对已知位点的侧翼序列进行分析或克隆,以研究基因的遗传表达调控。
In modern research of molecular biology, we usually need to analyse or clone these flanking sequence in given sites, so as to study gene expression and control.
因此,利用CBF1基因进行植物遗传改良时应根据物种的应用特点采用合适的表达调控策略。
The degree of the effects depended on the expression level CBF1. Proper regulation strategy for gene expression should be concerned when using CBF1 to modified plants.
组蛋白赖氨酸甲基化在基因表达调控中的作用已成为表观遗传学研究的热点。
The role of histone lysine methylation in the gene expression regulation has turned into the hotspot of epigenetics.
它是一个吵闹的勾当!:在纳摩尔级别上的基因调控〉,《遗传学趋势》15(1999年):第65-69页。
McAdams, Arkin. "It's A Noisy Business! : Gene Regulation at the Nanomolar Scale. " Trends in Genetics 15 (1999): 65-69.
组蛋白赖氨酸的甲基化在真核基因表观遗传调控中起着关键作用。
Histone lysine methylation plays a key role in epigenetic regulation of eukaryotic genes.
HLA是迄今所知最为复杂的遗传多态性系统,是调控人体特异性免疫应答和决定疾病易感性个体差异的主要基因系统。
HLA is the most polymorphic gene complex of all human genetic systems, play a key role in specific immune response, determine the heterogeneity of individual associated with disease.
这种差异可能是由遗传、环境、疾病状态或饮食结构等诸多因素引起的。其中基因(遗传)多态性是导致药物代谢个体差异的较为常见且不可调控的因素。
The individual variation may be caused by many factors, such as genetics, environment, disease stage and diet, etc, among which genetic polymorphism is a common and uncontrollable factor.
组蛋白赖氨酸甲基化是组蛋白尾段发生的一种重要共价修饰,在基因的表观遗传转录调控中起着关键的作用。
The methylation of histone lysine is an important covalent modification at its tails and plays a key role in epigenetic regulation.
CYP450的合成受着遗传基因的调控,一旦基因发生变异,它所调控合成的CYP450酶及酶所催化的药物代谢即发生变化。
CYP450 is regulated by genetic genes. Once the gene mutates, the CYP450 enzyme that coded and the drug metabolism then will change.
虽然蛋壳颜色具有较高的遗传力,受多个基因共同调控,但是饲料营养素也可以影响蛋壳颜色。
Although the eggshell color is a property with a high heritability and controlled by multiple genes, feed nutrients can influence eggshell color.
以及运用遗传学的方法分析蛋白质的功能、基因的调控与遗传性的疾病。
Use of genetic methods to analyze protein function, gene regulation and inherited disease.
以酵母为模式生物,利用表观遗传,分子遗传和生物化学等手段,研究表观遗传调控在维持基因组稳定性中的作用。
Using yeast as model organism, study the contribution of epigenetic regulation to the maintenance of genomic stability, by epigenetic, molecular genetic and biochemic approaches.
炎症反应中t辅助细胞的分化,细胞因子、趋化因子等基因的表达都受到表观遗传的调控。
In inflammation responses, differentiation of t helper cells and gene expression of cytokine and chemokine are all regulated by epigenetics.
表观遗传调控可以影响基因转录活性而不涉及DNA序列的改变。
An epigenetic event alters the activity of genes without changing their structure.
近年来 ,关于FecB基因的遗传及生理效应、基因图谱的绘制以及对绵羊卵泡发育和排卵率调控机制的研究取得了很大进展。
The Study about the Fec B genes genetic and physiological effect, genetic mapping, regulation on oocyte development and ovulation rate have made the mighty advance in recent years.
近年来 ,关于FecB基因的遗传及生理效应、基因图谱的绘制以及对绵羊卵泡发育和排卵率调控机制的研究取得了很大进展。
The Study about the Fec B genes genetic and physiological effect, genetic mapping, regulation on oocyte development and ovulation rate have made the mighty advance in recent years.
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