• 本研究组主要从事基因表达调控结构生物学研究

    The main research focus of our group is on structural studies of gene expression and regulation.

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  • 植物碱性亮氨酸拉链蛋白高等植物基因表达调控重要作用

    Plant basic leucine zipper proteins play an important role in the expression and regulation of higher plant genes.

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  • 综述近年来哺乳动物胚胎着床前发育阶段基因表达调控研究进展。

    This review summaries current development on the gene expression and control of mammalian preimplantation embryo.

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  • 本文对骨桥蛋白肿瘤中的信号转导基因表达调控以及肿瘤转移过程中的作用予以综述

    This article reviews its role in the signal transduction, expression and regulation in tumors and the roles in tumor metastasis.

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  • 生物化学分子生物学研究进展了简要评述,包括分子的结构、酶的催化反应机制、酶基因表达调控等。

    Advances in biochemical and molecular biological studies, including enzyme structure, catalytic mechanism and gene expression and regulation of peroxidases are reviewed.

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  • 本文主要介绍棉纤维不同发育阶段纤维素合成特点,纤维素合成的场所底物代谢模型基因表达调控研究进展

    In this review, the progresses about the site, substrate, gene expression and regulation, and a carbon metabolism model of cellulose synthesis in developing cotton fibers were discussed.

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  • 调控分子这个开关dna结合时,相邻基因便开始表达终止表达

    When regulatory molecules bind to this switch DNA, the contiguous gene is either expressed or prevented from being expressed.

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  • hcbp6同源基因克隆化为研究不同种属来源的HCBP6基因结构功能表达调控等研究奠定了基础。

    The successful cloning of monkey HCBP6 gene paves a way for the study of the relationship of structure and function of HCBP6 genes from different species.

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  • 激活低氧诱导因子(HIF - 1),从而调控一系列缺氧相关基因表达

    Hypoxia activates hypoxia-inducible factor 1 (HIF-1), thus it controls a series of expression of genes correlated with hypoxia.

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  • 本文AP2/EREBP转录因子结构特征功能靶元件的作用模式基因调控表达以及最新研究进展做全面性的综述。

    The review is about structure character, function, interacting mode, genes regulation expression of AP2/EREBP transcription factors and its novel research.

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  • 本文就结构功能基因表达调控以及应用前景作一综述

    Its structure, function and regulation of gene expression and application prospect are introduced comprehensively here.

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  • 因此进一步明确PTEN基因胶质瘤中的表达调控机制有助于我们深入了解PTEN在胶质瘤发生中的作用

    Then, study on the expression and regulation of PTEN in gliomas will help to further understand the function of PTEN in glioma.

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  • 结果芯片结果显示实验组已知功能差异表达基因16条其中下调基因13条4条内分泌调控密切相关。

    Results 16 identified genes expressed differently, including 13 down-regulated in which 4 were related to endocrine regulation.

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  • 要阐明各种信号传递途径基因表达调控机理克隆鉴定转录因子关键

    One of the keys to understand the molecular mechanism of gene expression and the pathway of signal transduction is to clone and identify the transcription factors.

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  • 目的探讨肺癌细胞株对化疗药物敏感性药相关基因凋亡调控基因表达关系

    Objective To explore the relationship of chemotherapy sensitivity and expression of multidrug resistance genes and apoptosis regulation genes in human lung cancer cell lines.

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  • 文章综述LPL基因结构功能表达调控以及复杂疾病关联研究进展。

    Here we review the structure, function, expression regulation of the LPL gene along with its association with complex diseases.

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  • 本文介绍了前列腺内过氧化物合酶2基因结构表达调控机理及其繁殖性能的关系。

    In this paper, we briefly introduced the structure, expression, regulation mechanism of prostaglandin-endoperoxide synthase 2 gene and the relationship between this gene and reproductive performance.

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  • 目的观察饮食饲养造成肝脏胰岛素抵抗肝糖输出有关的调控基因表达关系

    Objective To study the relationship between hepatic insulin resistance induced by high fat diet and the expression of genes involving hepatic glucose output.

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  • 目的探讨乳腺癌细胞化疗敏感性耐药相关基因凋亡调控基因表达关系

    Objective To explore the relationship of chemotherapy sensitivity and expression of multidrug resistance genes and apoptosis regulation genes in human breast cancer cell lines.

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  • 蛋白乙酰化修饰基因表达调控相关,各种肺部疾病病变过程

    The acetylation of histone is related to gene expression and regulation, which takes part in the pathological courses of all kinds of lung diseases.

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  • 组蛋白脱乙酰基酶蛋白乙酰基酶抑制剂通过对组蛋白乙酰化水平的调控影响特定基因表达,改变细胞周期的进程。

    HDAC and histone deacetylase inhibitors (HDI) can affect expression of some specific genes and induce cell differentiation growth arrest and apoptosis through regulating histone acetylation level.

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  • 转录因子DNA相互作用基因表达调控系统的重要组成部分。

    The interaction between transcription factors and their DNA recognition sites are important for the regulation of the network that controls gene expression.

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  • 近年来随着基因动物制备技术日趋成熟完善,建立转基因动物模型已经成为研究真核基因表达调控一种重要手段

    Recently, with the development of transgenic technology, producing transgenic animal model has become an important way to study the expression regulation of eukaryotic genes.

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  • 本文果胶产生菌、果胶酶的理化性质、已克隆的果胶酶基因基因表达与调控果胶酶的用途等方面简述了微生物果胶酶研究进展。

    The present review features the pectinase from microorganisms, its physical and chemical characteristics, the genes of pectinase and its expression, and its applications were also stated.

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  • 结果:芯片结果显示实验组已知功能差异表达基因16条其中下调基因13条5条物质能量代谢调控密切相关

    Results: 16 identified genes expressed differently, including 13 down-regulated in which 5 were related to substance and energy metabolism.

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  • QTL环境的互作效应qtl的效应多次地被检测到,表明数量性状基因表达显著地受到环境的调控

    QE effects were detected more often than QTL main effects, might indicate that gene expression for quantitative trait could be greatly affected by environments.

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  • 因此选择对基因表达具有重要功能1其上游的调控区及下游外显子内含子交界序列通过直接测序法进行SNP筛查,进一步分析多态位点病窦的关联性

    Therefore the other aim of our study is to discover SNPs of HCN4 exon 1, including the regulatory sequence and exon-intron boundary of it, which plays an importable role of channel function.

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  • 文章介绍了嗅觉受体基因结构表达调控分布分子进化及其多态性研究进展, 并讨论了该基因嗅觉功能嗅觉障碍的关系。

    The main gene related with olfaction was olfactory receptor (OR) gene. This review introduced the structure, expression regulation, distribution, molecular evolution and polymorphism of OR gene.

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  • LRP16基因表达垂体泌乳素腺瘤细胞增殖活性存在相关关系,LRP16基因可能垂体泌乳素腺瘤细胞增殖调控

    The expression of LRP16 is correlated with cell Proliferation of Prolactinomas and LRP16 may contributet to the regulation of cell Proliferating.

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  • LRP16基因表达垂体泌乳素腺瘤细胞增殖活性存在相关关系,LRP16基因可能垂体泌乳素腺瘤细胞增殖调控

    The expression of LRP16 is correlated with cell Proliferation of Prolactinomas and LRP16 may contributet to the regulation of cell Proliferating.

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