本研究组主要从事基因表达与调控的结构生物学研究。
The main research focus of our group is on structural studies of gene expression and regulation.
植物碱性亮氨酸拉链蛋白在高等植物基因表达与调控中起重要作用。
Plant basic leucine zipper proteins play an important role in the expression and regulation of higher plant genes.
综述近年来哺乳动物胚胎着床前这一发育阶段基因表达与调控的研究进展。
This review summaries current development on the gene expression and control of mammalian preimplantation embryo.
本文对骨桥蛋白在肿瘤中的信号转导、基因表达与调控以及肿瘤转移过程中的作用予以综述。
This article reviews its role in the signal transduction, expression and regulation in tumors and the roles in tumor metastasis.
的生物化学与分子生物学研究进展作了简要评述,包括酶分子的结构、酶的催化反应机制、酶基因表达与调控等。
Advances in biochemical and molecular biological studies, including enzyme structure, catalytic mechanism and gene expression and regulation of peroxidases are reviewed.
本文主要介绍了棉纤维不同发育阶段纤维素合成的特点,纤维素合成的场所、底物,碳代谢模型,基因表达与调控的研究进展。
In this review, the progresses about the site, substrate, gene expression and regulation, and a carbon metabolism model of cellulose synthesis in developing cotton fibers were discussed.
当调控分子与这个开关dna结合时,相邻的基因便开始表达或终止表达。
When regulatory molecules bind to this switch DNA, the contiguous gene is either expressed or prevented from being expressed.
猴hcbp6同源基因的克隆化为研究不同种属来源的HCBP6基因的结构域功能、表达与调控等研究奠定了基础。
The successful cloning of monkey HCBP6 gene paves a way for the study of the relationship of structure and function of HCBP6 genes from different species.
低氧可激活低氧诱导因子(HIF - 1),从而调控一系列与缺氧相关基因的表达。
Hypoxia activates hypoxia-inducible factor 1 (HIF-1), thus it controls a series of expression of genes correlated with hypoxia.
本文就AP2/EREBP类转录因子的结构特征、功能、与靶元件的作用模式、对基因的调控表达以及最新研究进展做全面性的综述。
The review is about structure character, function, interacting mode, genes regulation expression of AP2/EREBP transcription factors and its novel research.
本文就其结构与功能、基因表达的调控以及应用前景作一综述。
Its structure, function and regulation of gene expression and application prospect are introduced comprehensively here.
因此进一步明确PTEN基因在胶质瘤中的表达与调控机制,有助于我们深入了解PTEN在胶质瘤发生中的作用。
Then, study on the expression and regulation of PTEN in gliomas will help to further understand the function of PTEN in glioma.
结果芯片结果显示实验组已知功能差异表达基因有16条。其中下调基因有13条,4条与内分泌调控密切相关。
Results 16 identified genes expressed differently, including 13 down-regulated in which 4 were related to endocrine regulation.
要阐明各种信号传递途径与基因表达调控的机理,克隆和鉴定转录因子是关键。
One of the keys to understand the molecular mechanism of gene expression and the pathway of signal transduction is to clone and identify the transcription factors.
目的探讨人肺癌细胞株对化疗药物的敏感性与多药耐药相关基因和凋亡调控基因表达的关系。
Objective To explore the relationship of chemotherapy sensitivity and expression of multidrug resistance genes and apoptosis regulation genes in human lung cancer cell lines.
文章综述了LPL基因的结构、功能、表达调控以及与复杂疾病的关联研究进展。
Here we review the structure, function, expression regulation of the LPL gene along with its association with complex diseases.
本文介绍了前列腺素内过氧化物合酶2基因的结构、表达、调控机理及其与繁殖性能的关系。
In this paper, we briefly introduced the structure, expression, regulation mechanism of prostaglandin-endoperoxide synthase 2 gene and the relationship between this gene and reproductive performance.
目的观察高脂饮食饲养造成的肝脏胰岛素抵抗与肝糖输出有关的调控基因表达的关系。
Objective To study the relationship between hepatic insulin resistance induced by high fat diet and the expression of genes involving hepatic glucose output.
目的探讨人乳腺癌细胞化疗敏感性与多药耐药相关基因和凋亡调控基因表达的关系。
Objective To explore the relationship of chemotherapy sensitivity and expression of multidrug resistance genes and apoptosis regulation genes in human breast cancer cell lines.
组蛋白乙酰化修饰与基因的表达调控相关,参与了各种肺部疾病的病变过程。
The acetylation of histone is related to gene expression and regulation, which takes part in the pathological courses of all kinds of lung diseases.
组蛋白脱乙酰基酶与组蛋白脱乙酰基酶抑制剂通过对组蛋白乙酰化水平的调控,影响特定基因的表达,改变细胞周期的进程。
HDAC and histone deacetylase inhibitors (HDI) can affect expression of some specific genes and induce cell differentiation growth arrest and apoptosis through regulating histone acetylation level.
转录因子与DNA的相互作用是基因表达调控系统的重要组成部分。
The interaction between transcription factors and their DNA recognition sites are important for the regulation of the network that controls gene expression.
近年来,随着转基因动物制备技术的日趋成熟与完善,建立转基因动物模型已经成为研究真核基因表达调控的一种重要手段。
Recently, with the development of transgenic technology, producing transgenic animal model has become an important way to study the expression regulation of eukaryotic genes.
本文从果胶酶的产生菌、果胶酶的理化性质、已克隆的果胶酶基因、基因的表达与调控及果胶酶的用途等方面简述了微生物果胶酶的研究进展。
The present review features the pectinase from microorganisms, its physical and chemical characteristics, the genes of pectinase and its expression, and its applications were also stated.
结果:芯片结果显示实验组已知功能差异表达基因有16条,其中下调基因有13条,5条与物质能量代谢调控密切相关。
Results: 16 identified genes expressed differently, including 13 down-regulated in which 5 were related to substance and energy metabolism.
QTL与环境的互作效应比qtl的主效应更多次地被检测到,表明数量性状基因的表达显著地受到环境的调控。
QE effects were detected more often than QTL main effects, might indicate that gene expression for quantitative trait could be greatly affected by environments.
因此选择对基因的表达具有重要功能的外显子1和其上游的调控区及下游外显子内含子交界区序列通过直接测序法进行SNP筛查,并进一步分析多态位点与病窦的关联性。
Therefore the other aim of our study is to discover SNPs of HCN4 exon 1, including the regulatory sequence and exon-intron boundary of it, which plays an importable role of channel function.
文章介绍了嗅觉受体基因的结构、表达调控、分布、分子进化及其多态性研究进展, 并讨论了该基因与嗅觉功能和嗅觉障碍的关系。
The main gene related with olfaction was olfactory receptor (OR) gene. This review introduced the structure, expression regulation, distribution, molecular evolution and polymorphism of OR gene.
③LRP16基因的表达量与垂体泌乳素腺瘤细胞增殖活性存在相关关系,LRP16基因可能参与垂体泌乳素腺瘤细胞增殖的调控。
The expression of LRP16 is correlated with cell Proliferation of Prolactinomas and LRP16 may contributet to the regulation of cell Proliferating.
③LRP16基因的表达量与垂体泌乳素腺瘤细胞增殖活性存在相关关系,LRP16基因可能参与垂体泌乳素腺瘤细胞增殖的调控。
The expression of LRP16 is correlated with cell Proliferation of Prolactinomas and LRP16 may contributet to the regulation of cell Proliferating.
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