本文综合讨论了目前基因组中基因功能注释存在的问题及解决这些问题的策略与方法。
In this paper, drawbacks in the annotation of gene function currently used in genomics and some strategies beneficial to the annotation of gene function are discussed.
结构注释是所有基因组学的基础，因为没有准确的基因模型，跨分类群理解基因功能或基因进化可能是受阻碍的。
Structural annotation is the foundation of all genomics as without accurate gene models understanding gene function or evolution of genes across taxa can be impeded.
搜索结果通常被用于各种功能基因组学和比较基因组学任务，例如注释未知序列，研究基因模型和比较两个序列集合。
The search results are commonly adopted for various functional and comparative genomics tasks such as annotating unknown sequences, investigating gene models and comparing two sequence sets.
植物基因组序列的注释能够被分成结构注释和功能注释。
Annotation of plant genomic sequences can be separated into structural and functional annotation.
功能注释高度依赖于与其他已知基因或蛋白质的序列相似性，因为在一个基因组规模上的大多数最初的“首过”功能注释是可传递的。
Functional annotation is highly dependent on sequence similarity to other known genes or proteins as the majority of initial "first-pass" functional annotation on a genomic scale is transitive.
以一种比较方式进行跨基因组的联合结构注释和功能注释促进了更准确的注释以及对基因和基因组进化的一个理解。
Coupling structural and functional annotation across genomes in a comparative manner promotes more accurate annotation as well as an understanding of gene and genome evolution.
以一种比较方式进行跨基因组的联合结构注释和功能注释促进了更准确的注释以及对基因和基因组进化的一个理解。
Coupling structural and functional annotation across genomes in a comparative manner promotes more accurate annotation as well as an understanding of gene and genome evolution.
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