48小时以后，他给老鼠们注射含有Math1基因的腺病毒。
Forty-eight hours later, he injects the animals with adenoviruses containing Math1 genes.
目的研究携带血管抑素K1-5基因的腺病毒载体对其对血管内皮细胞增殖的抑制作用。
Objective To investigate the suppression effects of a adenovirus vector containing angiostatin K1-5 gene to the proliferation and migration of vascular endothelial cells.
方法将携带P16基因的腺病毒体外转染人膀胱癌t 24细胞，观察腺病毒对T24细胞的转染效率以及P 16基因修饰的T24细胞体外生物学特性的改变。
Methods P16 genes were delivered to the T24 cells jn vitro by adenovirus vectors. Gene transfer efficiency and changes of biological specificity of T24 cells were analyzed.
格鲁曼和同事们把I型和II型干扰素基因转入一种腺病毒中，这种腺病毒是他们注射到多群猪中的。
Grubman and his colleagues introduced type I and type II interferon genes into an adenovirus, which they administered to groups of pigs.
当时，医生们仅仅披露，使用“腺病毒”或者感冒病毒将HIV的基因植入人体的疫苗没有发生作用。
At the time, doctors revealed only that the vaccine-which USES an "adenovirus," or the common cold virus, to deliver HIV genes into the body-had not worked.
Chiu补充说，伶猴腺病毒(TMAdV)在人类身上罕见，这让它可能成为一个潜在的强大工具，在基因治疗中充当病毒载体。
TMAdV's rarity in humans could make it a potentially powerful tool as a viral vehicle for delivering gene therapy, Chiu adds.
Cerepro被固定在一个腺病毒(一种能够携带双链形式的DNA病毒)上来传染基因，这个基因负责产生胸苷激酶这种蛋白质。
Cerepro harnesses an adenovirus, a type of virus which carries its DNA in double-stranded form, to transmit a gene responsible for the production of a protein called thymidine kinase.
人们希望，改构后的腺病毒在基因治疗方面能起到重要的作用，例如，作为载体基因携带治疗性基因到达细胞内。
The hope is that modified adenovirus could play a role in gene therapy, used as a vector (carrier) for delivering therapeutic genes to the interior of cells.
腺病毒载体是继逆转录病毒载体后在基因治疗、基因免疫等方面应用开发得较早且较成熟的一种基因载体。
Adenovirus vector is an earlier and maturer genetic carrier in the respect of gene therapy and genetic immunization after retroviral vector.
在此，我们研究了用白介素(IL) - 13进行腺病毒载体基因治疗的效果，白介素(IL) - 13是一种在急性肾移植损伤中有强大免疫调节特性的细胞因子。
Here we investigate the effects of adenovirus-mediated gene therapy with interleukin (IL) -13, which is a cytokine with strong immunomodulatory properties, on acute renal allograft injury.
目的：评估在腺病毒介导下，由蛋白涂层金属支架向局部动脉壁转基因的可行性、效率和选择性。
Objective: to assess the feasibility, efficiency and selectivity of adenovirus mediated gene transfer to local arterial wall by protein coated metallic stent.
结论：构建的心肌特异性表达腺病毒载体可使外源基因在心肌细胞内特异性表达。
Conclusion: the established viral vector AdmlcGFP allows heart specific expression of a foreign gene.
结果：与野生型腺病毒相比，重组腺病毒能显著地提高目的基因在四种不同肿瘤细胞中的表达。
Results Fiber-mutant adenovirus vector showed a notably enhanced gene expression in four different tumor cells compared with that of conventional ones.
目的：研究腺病毒介导的鼠内皮抑素基因对胃癌的治疗作用。
Objective: to study the inhibitory effects on gastric cancer by adenoviral transduction of mouse endostatin gene.
腺病毒作为新兴的载体因其转染效率和表达效率高而日益受到重视，成为肿瘤基因治疗的主要载体之一。
As the newly emerging vector, recombinant adenovirus is being given more attention and has become the major vector of gene therapy because of its high rate of transfection and expression.
目的：研究腺病毒介导的脑源性神经营养因子(BDNF)基因在大鼠损伤脊髓内的表达规律，观察外源性BD NF对损伤脊髓的作用。
Objective: to investigate the effects of the expression of exogenous brain derived neurotrophic factors (BDNF) on injured spinal cord following in vivo adenoviral gene transfer to the cord.
目的探讨大鼠心脏移植过程中，重组腺病毒介导的外源基因转移至供心的可行性及安全性。
Objective to study efficiency and security of the recombinant adenoviral-mediated gene transfer to the donor heart during the heart transplantation.
方法建立人卵巢癌裸鼠动物模型，检测腺病毒介导的人血管抑素基因对肿瘤生长的抑制作用。
Methods A human ovarian cancer model using a nude mice was built to test the suppressive effect of human angiostatin gene mediated by adenovirus on the tumor growth.
E1 B基因缺陷腺病毒注射液作为基因治疗的一种手段近几年投入临床应用。
E1B gene-deleted adenovirus injection is put into clinical apply from several years ago as a gene therapy method.
目的：构建表达小鼠轮状病毒（EDIM）EW株VP7基因的重组腺病毒，以在小鼠模型上研究轮状病毒的免疫保护机制。
Objective:To construct a replication defective recombinant adenovirus expressing murine rotavirus(EDIM)EW strain VP7to recruit it in studies on the protective immunization of rotavirus.
利用基因重组原理，构建可表达CNTF的腺病毒。
The CNTF recombinant Adenovirus was constructed using the Adenovirus system.
目的：构建携带内皮抑素基因的增殖型腺病毒载体，寻找结肠癌的有效治疗方法。
Objective: To construct a replication-competent adenovirus vector carrying human endostatin gene, looking for an effective method for the therapy of colon cancer.
目的：观察腺病毒介导的基因转移在乳腺癌细胞的转导效率及腺病毒转导对细胞生长的影响。
Objective: To observe the transduction efficiency of adenoviral-mediated gene transfer in human breast cancer cells and the effect of viral transduction on the growth of the cancer cells.
目的利用细菌内同源重组法构建含ICOS胞外区基因的重组腺病毒。
Objective To construct the recombinant adenovirus of human ICOS extracellular domain gene by using the method of homologous recombination in bacteria.
目的研究联合运用狂犬病毒糖蛋白基因重组腺病毒与同一抗原核酸疫苗对小鼠的免疫效果。
Objective To investigate the immune response of mice primed by DNA particle bombing and boosted by immunization with replication-defective adenoviral recombinant bearing rabies glycoprotein gene.
摘要腺病毒载体具有高效转染和低细胞毒性的特点，已成为基因治疗研究中应用最广泛的载体之一。
Adenovirus vectors have the characteristics of high transfection efficiency and low cytotoxicity, and they have become most widely used vectors for gene therapy.
摘要腺病毒载体具有高效转染和低细胞毒性的特点，已成为基因治疗研究中应用最广泛的载体之一。
Adenovirus vectors have the characteristics of high transfection efficiency and low cytotoxicity, and they have become most widely used vectors for gene therapy.
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