目的探讨乙型肝炎病毒（HBV）作为肝靶向性基因治疗载体的可能性。
Objective To evaluate the possibility of hepatitis B virus (HBV) as a vector in liver-targeting gene therapy.
逆转录病毒是最常用的基因治疗载体，但对人类细胞的基因导入率较低。
Retrovirus (RV) is the most widely used vector for gene transfer, but its efficiency is very low for human cells.
麻省理工学院的科学家报道了一类新型的可降解多聚物作为基因治疗载体的合成和试验室检测。
MIT scientists are reporting synthesis and laboratory tests of a promising new group of degradable polymer delivery vehicles for gene therapy.
目的探索H BV作为基因治疗载体的可能性及检验HBV点突变表达显性阴性突变体抗hbv的作用。
Objective to explore the possibility of using HBV as a gene delivery vector, and to test the anti-HBV effects by intracellular expression of dominant negative mutants of core protein.
目的探索利用乙型肝炎病毒(HBV)作为基因治疗载体的可能性及检验其表达反义rna抗hbv的作用。
Objective to explore the possibility of using HBV as a gene delivery vector, and to test the anti-HBV effects by intracellular expression of antisense RNA.
因为这项试验首次利用基因治疗载体导入人类视网膜进行眼睛治疗，所以该队伍已经进行了大量的临床前试验。
As this trial is the first to treat an eye disease using administration of gene therapy vectors to human retinas, the team have carried out extensive pre-clinical testing.
壳聚糖是一种天然的生物可降解性，生物相容性好而且安全无毒的多糖，因而它成为基因治疗载体研究的热点。
Recently chitosan is focused in the research of gene delivery system for it is already known as a biocompatible, biodegradable and non-toxic polysaccharide.
Chiu补充说，伶猴腺病毒(TMAdV)在人类身上罕见，这让它可能成为一个潜在的强大工具，在基因治疗中充当病毒载体。
TMAdV's rarity in humans could make it a potentially powerful tool as a viral vehicle for delivering gene therapy, Chiu adds.
很多基因治疗的其他问题出在携带基因的载体上，通常是病毒。
Many of gene therapy's other problems have been with the vector that carries the gene, usually a virus.
为解决这个难题，MIT的研究者开发了一种和病毒载体同样有效，然而却似乎没什么风险的新的聚合物作为基因治疗的载体。
To solve that problem, MIT researchers have developed a new polymer for gene therapy that is as effective as viruses, the standard carriers, but it seems to have none of the risks of viral treatments.
基因治疗能否成功最终取决于这些基因的运输载体。
The success of gene therapy ultimately depends on these gene delivery vehicles or vectors.
人们希望，改构后的腺病毒在基因治疗方面能起到重要的作用，例如，作为载体基因携带治疗性基因到达细胞内。
The hope is that modified adenovirus could play a role in gene therapy, used as a vector (carrier) for delivering therapeutic genes to the interior of cells.
在此，我们研究了用白介素(IL) - 13进行腺病毒载体基因治疗的效果，白介素(IL) - 13是一种在急性肾移植损伤中有强大免疫调节特性的细胞因子。
Here we investigate the effects of adenovirus-mediated gene therapy with interleukin (IL) -13, which is a cytokine with strong immunomodulatory properties, on acute renal allograft injury.
有效并且安全的靶向性载体是基因治疗能否成功的关键。
Effective and secure targeted vector is the key of the gene therapy succeed or not.
另外，杆状病毒是非复制型载体，能高效表达目的蛋白，其作为基因转移载体在基因治疗中乙显示出良好的应用前景。
Additionally, baculovirus has been a new gene transfer vector used in gene therapy due to its advantages of the extremely high expression of foreign genes and being non-reproduce vector.
腺病毒载体是继逆转录病毒载体后在基因治疗、基因免疫等方面应用开发得较早且较成熟的一种基因载体。
Adenovirus vector is an earlier and maturer genetic carrier in the respect of gene therapy and genetic immunization after retroviral vector.
而载体的选择是基因治疗的关键，所以研究者们不遗余力的寻找安全、高效、稳定的基因载体。
But the genetic carrier is key point to gene therapy, consequently many researchers spare no effort to find more safe, high performance and stable genetic carrier.
目的探索逆转录病毒载体在基因治疗乙型肝炎中的应用。
Objective To investigate the effectivness of recombined retrovirus vector in gene therapy.
目的筛选肝再生增强因子重组质粒基因治疗时较优的载体、途径和剂量及三者的最佳组合。
Objective To select an optimal combined set of carrier, introducing route and dose of recombinant plasmid of augmenter of liver regeneration (ALR) for ALR gene therapy.
目前，NSC在恶性脑肿瘤中基因治疗的应用，主要包括构建载体和包装病毒载体。
At present, the applications of NSC gene therapy of malignant brain tumor mainly includes the construction of carriers and the package of viral vectors.
结果树状聚合物可以增溶药物、作为药物和基因治疗的载体，并自身具有药理作用且较安全。
Results Dendrimers could solubilize drugs, serve as drug carriers in gene therapy, produce self-pharmacologic action.
杆状病毒载体将在未来药物研发、疫苗生产、基因治疗、重组杆状病毒杀虫剂等领域得到广泛应用。
The insect baculovirus, in the new century, will be applied in drug research and development, production of vaccines, gene therapy and recombinant baculovirus insecticides.
基因转移载体是基因治疗的重要组成部分，包括病毒载体和非病毒载体。
Gene transfer vector is the important ingredient in gene therapy, which includes virus vector and non-virus vector.
基因治疗是根治遗传性疾病的唯一方法，但是目前基因治疗遇到的最主要的困难之一就是载体问题。
Gene therapy is the only way to cure Mendelian hereditary disorders. However, one of the main problems at present is the vector.
肿瘤靶向基因治疗的主要目的是用靶向性的载体将治疗基因靶向传递到肿瘤细胞。
A major goal of tumor-targeting gene therapy is to transfer genes efficiently to tumor cells by targeted vectors.
目的：探讨慢病毒载体在白血病细胞中的基因转导效率，为白血病基因治疗提供关键依据。
Objective to investigate the gene transduction efficiency of lentiviral vector in leukemia cells to provide key basis for leukemia gene therapy.
目的：探讨慢病毒载体在白血病细胞中的基因转导效率，为白血病基因治疗提供关键依据。
Objective to investigate the gene transduction efficiency of lentiviral vector in leukemia cells to provide key basis for leukemia gene therapy.
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