该区的基因异质性程度在干扰素治疗后均有下降。
The degrees of gene tic heterogeneity were decreased by IFN treatment in our patients.
结论：基因异质性存在于hgv的E2区，干扰素治疗可减少基因异质性。
Conclusion: Genetic heterogeneity is existed in the E2 region of HGV and decreased by IFN therapy.
不同基因型决定相同表型的现象。参见等位基因异质性、临床异质性和基因座异质性。
Genetic lethal --- A mutant allele or genetically determined trait that leads to failure to reproduce, although not necessarily to death prior to reproduction.
结论CYP1B1基因具有明显的遗传异质性。
Conclusion Mutations in the CYP1B1 gene have genetic heterogeneity.
由于肿瘤发生的复杂性及患者的异质性，往往要将基因治疗与其它疗法相结合才能收到满意的疗效。
Because of the complexity of tumors and heterogeneity of human, gene therapy is often needed to combined with other therapies to obtain good effect.
CD44是单一基因所编码的具有高度异质性的单链膜表面糖蛋白家族，在各种组织中广泛表达。
CD44 is a highly heterogeneity family of cell surface proteoglycan, represent products of a single gene and widely expressing in various tissues.
表明，地方品种的抗性功能基因比育成品种异质性高。
The results showed the landrace were more heterogeneous than breeding cultivar in functional genes.
遗传性听力损害具有高度的遗传异质性，据估计与几百个基因有关。
Hereditary hearing impairment exhibits incredible genetic heterogeneity. It was estimated that several hundred genes associate with hereditary hearing impairment.
结论云南省G6PD基因具有明显异质性。
Conclusions The G6PD gene in Yunnan people is heterogeneous.
结论TTGE是筛选线粒体基因体细胞性同质性突变和各种比例异质性突变的一种敏感方法。
Conclusion TTGE is an effective method for screening acquired homoplasmic mitochondrial gene mutation and its different percentage.
该病具有遗传异质性，致病基因包含TSC1基因和TSC2基因，分别于1997年和1993年被克隆出。
TSC displays genetic heterogeneity with two known genes: TSC1 and TSC2, which was cloned in 1997 and 1993 respectively.
两基因座均存在序列异质性。
对每个肿瘤三个不同区域进行免疫组化和银原位杂交，以判定HER2基因扩增的区域异质性和遗传异质性。
Regional and genetic heterogeneity of HER2 gene amplification was determined in three different areas of each tumor by immunohistochemistry and silver in situ hybridization.
本文综述了药物基因组学的基本概念、高血压病和抗高血压药物反应异质性、与药物新陈代谢相关的基因、个体化治疗等方面的应用情况。
This review includes basic concepts of pharmacogenomics, heterogeneity of hypertension and antihypertensive drug responses, genes associate with drug metabolism, and individualized drug therapy.
通过分析肿瘤细胞的密度及等位基因突变的几率来确定肿瘤异质性和等位基因特异性突变的不平衡性。
Tumor cellularity and mutant allele frequency were analyzed to identify tumor heterogeneity and mutant allele-specific imbalance.
临床表型存在高度的异质性，是否与生活习惯或基因多态性有关有待进一步研究。
Further study is warranted to investigate the association of this heterogeneity with lifestyle or genetic information.
基于发表的文献，提供了有关基因座异质性、突变类型、临床和生化数据、地理位置和常见突变的信息。
Information on locus heterogeneity, type of mutation, clinical and biochemical data, geographical location and common mutations are furnished based on published literature.
该位点基因突变异质性水平与亲缘关系、抽搐发作的早现性和血浆乳酸检测值等临床表型存在相关性。
The mutant heteroplasmy levels are positively associated with genetic relationship, seizure anticipation, plasma lactate data and other clinical features.
一个基因组的深度测序对一个个体或一个群体的异质性是非常有用的。
Sequencing a genome to great depth can be highly informative about heterogeneity within an individual or a population.
等位基因突变几率预测肿瘤异质性方面低于预期，但等位基因突变几率预测等位基因特异性突变不平衡性方面则高于预期。
Lower than expected mutant allele frequency indicated tumor heterogeneity, while higher than expected mutant allele frequency indicated mutant allele-specific imbalance.
提示I164T突变可能不是本组2型糖尿病的重要遗传因素，且该基因位点突变具有种族异质性。
The result reveals that I164T mutation is not a major predisposing genetic factor for type 2 diabetes and the mutation in adiponectin gene is different in rac…
提示I164T突变可能不是本组2型糖尿病的重要遗传因素，且该基因位点突变具有种族异质性。
The result reveals that I164T mutation is not a major predisposing genetic factor for type 2 diabetes and the mutation in adiponectin gene is different in rac…
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