接着，他们用另外的工程删除在肺部接收胸腺基质淋巴细胞生成素的感受器分子的基因。
Then they used additional engineering to delete the gene for the receptor molecule which picks up TSLP in the lungs.
每一个探针与一种特定基因的RNA绑定——它含有了一整套化学物质和基质的集合。
Each probe binds to the RNA of a specific gene-the one that contains a complementary set of chemical units, or bases.
目的：探讨基质金属蛋白酶10 (MMP10)基因及其蛋白在人自然流产蜕膜中的表达水平及临床意义。
Objective: To discuss expression levels of MMP10 gene and protein in human spontaneous abortion deciduas and its significance in clinic.
转录最高的基因与功能相关，如细胞粘附，基质蛋白，生长因子，受体和蛋白酶。
The most highly transcribed genes relate to functional groupings such as cell adhesion, matrix proteins, growth factors and receptors, and proteases.
而那些低表达的基因，功能涉及转录调节、小泡运输、铁代谢、信号转导，以及细胞外基质的组成和生物转化。
The genes with lower expression function in areas such as transcription regulation, vesicular transport, iron metabolism, signal transduction, and extracellular matrix organization and biogenesis.
利用基因转染方法使细胞获得不死性，快速建立小鼠胸腺基质细胞（MTSC）系。
For rapid establishment of mouse thymic stromal cell(MTSC) lines, gene transfection was used to immortalize fresh viable cells.
目的：探讨我国多发性骨骺发育不良患者中软骨寡聚物基质蛋白（COMP）基因的突变情况。
Objective: Our aim was to study the characteristics of mutation of cartilage oligomeric matrix protein (COMP) gene in Chinese patients with multiple epiphyseal dysplasia( MED).
目的：探讨造血基质细胞对人外周血干细胞体外培养扩增及基因转导的促进作用。
Objective: to inquire into the promoting effect of hematopoietic stromal cells on the culture and ex vivo expansion and the gene transduction of human peripheral blood stem cells.
目的：克隆人牙本质基质蛋白1 (DMP1)成熟肽编码区基因片段。
Aim: Cloning and partially sequencing of human dentin matrix protein 1 (DMP1) encoding mature protein.
目的：构建基质金属蛋白酶9靶向的RNA干扰质粒载体，观察其对小鼠巨噬细胞基质金属蛋白酶9基因表达的沉默作用。
AIM: to construct plasmid vector of RNA interference specific for matrix metalloproteinases (MMP) -9 and observe the silencing effect on gene expression of MMP-9 in macrophage of mice.
目的：探讨细胞外基质蛋白1基因在结直肠癌中的表达及其意义。
AIM: To investigate the expression and significance of the ECM1 gene in colorectal cancer tissue.
目的：研究基质金属蛋白酶7基因(MMP 7)在胃癌组织及不同分化程度的胃癌细胞中的表达情况，探讨其临床意义。
Purpose: to study the expression of MMP 7 gene in gastric cancer tissue and different stomach cancer cell line and explore its clinical significance.
目的：克隆小鼠牙胚组织中釉基质丝氨酸蛋白酶(EMSP1)成熟肽编码区基因。
Objective: To clone cDNA of enamel matrix serine proteinase (EMSP1) encoding mature protein from mouse dental germs.
结论骨巨细胞瘤中的多核巨细胞可能是由单核基质细胞融合而成，ADAM12基因参与了这一融合过程。
Conclusion Multinucleated giant cells probably originated from the fusion of mononuclear stromal cells and ADAM12 may participate in the fusion process.
目的：探讨白细胞介素6 (IL - 6)基因转染的骨髓基质细胞系qxmsc1 IL - 6对骨髓移植后造血功能的重建作用。
Objective: to study the effect of the IL-6 transfected bone marrow stromal cell, QXMSC1 IL-6, on the hematopoietic reconstitution in bone marrow transplanted mice.
结论：基质细胞的支持有维持造血干细胞原始造血活性及促进基因转导的双重好处。
Conclusion: the support exercised by the stromal cells would be of dual benefit to maintaining the primitive hematopoietic activity of hematopoietic stem cells and promoting the gene transduction.
结论罗格列酮可以通过调节MMP - 1和TIMP - 1的基因表达，抑制高糖导致的肾脏成纤维细胞外基质的蓄积。
Conclusion Rosiglitazone can adjust the mRNA expressions of MMP-1 and TIMP-1 and inhibit the cumulation of extracellular matrix in kidney fibroblasts induced by high glucose.
目的：了解基质金属蛋白酶9基因C1562T多态性与中国南方汉族人群不稳定型心绞痛易感性的关系。
AIM: to investigate the association between the matrix metalloproteinase-9 (MMP-9) gene C1562T polymorphism and the susceptibility to unstable angina pectoris (UAP) in Han population of South China.
目的：了解转录因子gata - 3基因在再生障碍性贫血(AA)和正常骨髓基质细胞(BMSC)中表达的情况，探讨AA发病的免疫机制。
AIM: to investigate the expression of transcription factor GATA-3 gene in the bone marrow stromal cells (BMSCs) from patients with aplastic anemia (AA) and normal controls.
因此，骨髓基质细胞被认为是一种理想的治疗性细胞和基因治疗中的靶细胞。
So the cells have been regarded as the ideal cells to be used for cell and gene therapy.
下面就牙本质基质蛋白- 1的表达定位、基因结构、生物学功能以及表达调控因素作一综述。
The expression orientation, gene structure, biological function and regulation of dentin matrix protein-1 in dentin and bone was reviewed in this paper.
目的研究类脂质蛋白沉积症一家系的细胞外基质蛋白1 (ECM1)基因突变。
Objective To study mutations in the extracellular matrix protein 1 (ECM1) gene in a family with lipoid proteinosis (LP).
结论成功建立了OPG基因修饰的骨髓基质细胞瞬时基因表达体系。
Conclusion The transiently expression system of BMSCs modified by OPG gene is successfully established.
目的探讨角膜基质细胞组织因子途径抑制物2 (TFPI - 2)的表达情况，为角膜新生血管的基因治疗提供方法。
Objective to observe the expression of TFPI-2 in corneal keratocytes in vitro and investigate the experimental basis for curing corneal neovascularization with gene-therapy.
背景：现阶段诱导骨髓基质细胞分化成骨的方法大致分为在化学药物作用、细胞因子作用以及转基因作用下的分化等。
BACKGROUND: the methods of inducing the differentiation of bone marrow stromal cells into osteoblasts included the differentiation under chemicals effect, cytokine effect and transgenosis.
结论：血管内皮生长因子基因转染可促进骨髓基质细胞的成骨分化。
CONCLUSION: Transfection with VEGF 165 gene can promote the osteogenic differentiation of cultured MSCs.
癌转移的过程涉及转移相关基因、细胞外基质、癌细胞运动和血管新生。
The complicated multistep processes of cancer metastasis are involved, refer to gene, extracellular matrix(ECM), motility of cancer cells and angiogenesis.
癌转移的过程涉及转移相关基因、细胞外基质、癌细胞运动和血管新生。
The complicated multistep processes of cancer metastasis are involved, refer to gene, extracellular matrix(ECM), motility of cancer cells and angiogenesis.
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