结论TNFA基因启动子区多态性与HBV感染结局显著关联。
Conclusion TNFA promoter polymorphisms are important host genetic factors affecting the outcomes of HBV infection.
目的：探讨RASSF1A基因启动子区甲基化与喉癌的关系。
Objective To investigate the relationship between promoter methylation of RASSF1A gene and laryngeal squamous cell carcinoma.
作为其中的一个工作，真核生物基因启动子区域的识别是一个难点。
As a part of which, the recognition of promoter field in eukaryote's gene is very hard.
目的本文旨在对NGAL基因启动子区及其附近是否存在TPA反应元件进行研究。
Objective the TPA response elements in NGAL promoter region and the sequences surrounding its promoter region will be determined.
目的：探讨中国汉族人群SLC6A4基因启动子区基因多态性与反社会人格障碍的关系。
Objective: To determine the association between the human SLC6A4 gene promoter polymorphism and the Chinese people with antisocial personality disorder(APD).
通常情况下，基因表达水平与DNA甲基化呈负相关，基因启动子区域甲基化从而导致该基因沉默。
Under usual conditions, there is an inverse correlation between gene expression level and DNA methylation. The gene can be silenced by DNA promoter methylation.
目的：分析甲基硝基亚硝基胍(MNNG)诱导的共表达蛋白的编码基因启动子区的转录因子结合部位。
AIM: to find out common transcription factor binding sites in the promoter regions of the encoding genes of the co-expressive proteins induced by N-methyl-N '-nitro-n - nitrosoguanidine (MNNG).
在NOS1基因启动子区鉴定了两个正调控区域和两个负调控区域，同时TS A可上调不同长度启动子的转录活性。
Two positive regulation regions and two negative regulation regions were found within NOS1 promoter. TSA may up-regulate the transcription activities of NOS1 promoters of different length.
例如，在植物里，其中的一个行为是在基因的启动子区域里开启和关闭其他基因。
In plants, for example, it is one of the things that switches other genes on and off at their promoter sites.
而且在基因的启动子区域里也找不到它们，它们却在基因自己转录的部分。
Nor were they found in the promoter regions of genes, but rather in the transcribed parts of the genes themselves.
从结构上来讲，基因包含三个区域：称为启动子的调节区域；与其并列的编码蛋白质的密码子区域；以及3'端尾部序列。
Structurally, a gene is formed by three regions: a regulatory region called the promoter juxtaposed to the coding region containing the protein sequence, and a “3’ tail” sequence.
被称为基因的启动子区域的共同特性是在转录开始时包含了一个由C字母和G字母交替重复的长序列。
It is a common characteristic of the so-called promoter regions of genes, where transcription begins, that they contain long, repetitive sequences of alternating Cs and Gs.
NALP1及其邻启动子区域显示出强烈的候选基因旌旗灯号。
NALP1 and its adjacent promoter region stood out strongly as the candidate gene.
最近有实验指出，肌动蛋白能被募集到基因的启动子区，是转录前起始复合物的成分。
Recently, it was reported that actin could be recruited to the promoter region of the gene, and is a component of pre-initiation complexes.
目的探讨纤溶酶原激活物抑制物-1（PAI- 1）启动子区基因多态性与脑卒中的关系。
Objective To investigate the relationship between the plasminogen activator inhibitor 1(PAI 1) promotor region gene polymorphism and cerebral stroke.
提示- 1892和- 1837两位点虽不在启动子区，但可能对靶基因表达具有一定的远端调控作用。
It suggests that although -1892 and -1837 loci are far from the promoter, they may play a remote regulation on the target gene expression.
为此本课题对载脂蛋白E基因及其启动子区—491A／T、—427T／C多态性进行了分析，旨在探讨其与国人AD的发病关系。
In the present study Apolipoprotein E (ApoE) gene and promoter -491A/T, -427T/C polymorphisms were investigated in order to understand the relationship with AD.
在启动子区域的DNA甲基化是抑制基因活性的一种重要机制。
DNA methylation in the promoter regions is a powerful mechanism for the suppression of gene activity.
这种现象主要在印迹基因和X染色体失活区域看到，这些区域中的启动子区的DNA甲基化导致了基因表达的抑制。
This phenomenon is mostly seen in imprinted genes and X-chromosome inactivation where DNA methylation of promoter regions leads to repression of gene expression.
该基因的启动子区有一个脱水应激元件DRE2和两个与调节早期防御反应有关的WRKY1盒。
There were a dehydration responsive element, DRE2 and two WRKY1 boxes, which was involved in adjusting the early-stage defense response.
而在基因的启动子区域里它们的影响和甲基胞核嘧啶正相反。
They also had the opposite effect from methylated cytosines found in promoter regions.
方法：运用甲基化特异性P CR，检测RASSF1A基因在48例喉癌组织、相对应癌旁组织及48例正常人外周血中的启动子区甲基化情况。
Methods a methylation-specific PCR was performed to detect the promoter methylation of RASSF1A gene in 48 tumor tissues, 48 corresponding normal tissues and 48 normal blood plasma.
在水稻胆碱激酶的启动子区发现有干旱应激元件DRE2，暗示该基因可能受脱水诱导。
A responsive element, DRE2 was found in the promoter region of the gene, which indicated that the choline kinase gene expression might be inducible by the dehydration.
方法采用RT P CR技术、硫化pcr结合限制性内切酶技术检测白血病细胞系及正常人外周血单个核细胞WT 1基因的表达及其启动子区DNA甲基化水平。
Method The expression of WT1 gene and its DNA methylation status were assayed in leukemia cell lines and normal peripheral blood mononuclear cells (PBMNC) by RT-PCR and MS-PCR.
结论鉴定了WNK4基因的启动子区，并对其功能进行了初步鉴定。
Conclusion the promoter region of the WNK4 gene was identified and its function was analyzed primarily.
结论鉴定了WNK4基因的启动子区，并对其功能进行了初步鉴定。
Conclusion the promoter region of the WNK4 gene was identified and its function was analyzed primarily.
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