如果发生基因丢失或被破坏，而这些变化又被传递到子代细胞，则可能会出现功能缺失或癌症等疾病。
If genes are missing or broken, these alterations are passed on to the new cell - and could result in disability or in diseases such as cancer.
感到惊奇是因为他们正期望这只是该工作很多步骤中的一个，包括一些可用来补偿CHOP基因丢失的东西。
They were surprised because they were expecting this to be just one of many processes at work, including some that might compensate for the loss of the CHOP gene.
一般情况下，它们都处于封存不动状态，但在特殊情况下，原癌基因被激活或抗癌基因丢失，人就会患上癌症。
Under normal circumstances, they are sealed in a fixed state, but in exceptional circumstances, the proto-oncogenes or tumor suppressor genes are activated is lost, people will suffer from cancer.
他们认为，如果这些沉默的基因以某种方式被重新激活，长期丢失的性状可能会重新出现。
If these silent genes are somehow switched back on, they argued, long-lost traits could reappear.
他们推断，虽然一些进化上的变化涉及基因的丢失，因此是不可逆转的，但其他的变化可能是基因被关闭的结果。
They reasoned that while some evolutionary changes involve the loss of genes and are therefore irreversible, others may be the result of genes being switched off.
整体结果丢失了一个假定的后期促进复合基因。
The overall result of this is the loss of a putative anaphase promoting complex gene.
那么丢失的基因哪里去了？
他们目前计划研究这些丢失基因的作用。
丢失的区域在各家庭之间有所不同，但是影响了至少六个在孤独症中起到重要作用的基因。
The missing regions varied among families, but they affected at least six genes that play a role in autism.
如果信息丢失，当荧光基因激活时，接收装置将会看到无法解读的混乱的颜色。
If the message fell into the wrong hands, the receiver would see a mix of colors once the genes were activated and be unable to read it.
换句话说，他们提供了人类在几千万年的进化中丢失的基因组。
In other words, they are making a list of DNA that has been lost from the human genome during millions of years of evolution.
提升带来了随岁月丢失的所有信息、基因和其他方面的恢复。
Ascension brings forth the recovery of all information lost over time, genetic and otherwise.
然而，在肿瘤中只有一个基因的单一复制出现突变，那就会增加突变的可能性而不仅仅是导致一个简单功能的丢失。
However, only a single copy of the gene is mutated in tumours, raising the possibility that the mutations do not result in a simple loss of function.
他们目前计划研究这些丢失基因的作用。早期的研究表明这些基因缺失可能与发育迟缓，自闭症和精神分裂症有关联。
They now plan to study the function of the missing genes. Previous studies have suggested that deletions of these genes may be linked with delayed development, autism and schizophrenia.
但是在该过程中，一些重要的，有价值的特性却丢失了，现在，科学家正利用基因技术逐步将这些特性重新寻回。
But in the process, important and useful traits have been lost, which scientists are now rediscovering using new gene technologies.
所有患有WAGR综合症的患者都缺少两个称为WT1和PAX6的基因，但是每一个个体也可以丢失其它附近的基因。
All people with WAGR syndrome lack two specific genes, called WT1 and PAX6, but each person can also be missing other nearby genes.
杂合性丢失是基因一个拷贝的正常功能丢失，同时另一个拷贝已经失活。
LOH is usually defined as the loss of normalfunction of one copy of a gene in which the other copy was already inactivated.
我们还发现，曾经含有但数百万年前已丢失内含子的基因的进化率也是很快的。
We also found that genes that hae lost their introns many millions of years ago eole especially fast near where the introns once resided.
引人注目的是，研究人员发现，大西洋鳕鱼的免疫系统丢失了许多被认为对于免疫系统是非常重要的基因。
Strikingly, the researchers found that Atlantic cod has lost genes that are essential for a critical component of its immune system.
随着水稻对气候改变及其它自然环境的适应，它的基因结构发生了改变，一些基因保留了，而另外一些则丢失了。
As rice adapted to climate changes and other natural circumstances, its genetic structure changed, keeping some genes and losing others.
脑膜瘤、神经鞘瘤、垂体腺瘤及转移瘤亦存在不同程度CDKN2基因的丢失。
The CDKN2 gene deletions were also detected in meningiomas, neurinomas, pituitary adenomas and metastatic carcinomas to a different degree.
UCSD研究者也对丢失肿瘤抑制基因的小鼠进行研究。肿瘤抑制基因可以阻止细胞生长。
The UCSD researchers also studied mice that were missing a tumor suppressor gene, which is a gene that ACTS to prevent cell growth.
表明该二体附加系的附加染色体能在杂种后代中稳定传递，不易因遗传排斥而丢失，可用来进行有关农艺性状的基因定位研究。
A conclusion could be made that the alien addition chromosomes in the disomic addition line can steadily pass on to its offspring, which can be used for gene mapping.
第10号染色体同源丢失性磷酸酶-张力蛋白基因(PTEN)作为肿瘤抑制基因，可以负性调节肿瘤细胞的生长。
As a tumor-suppressor gene, phosphatase and tensin homology deleted on chromosome 10 (PTEN) regulates negatively the growth of tumor cells.
结论：尼尔雌醇可以抑制IL6基因表达，从而抑制破骨细胞骨吸收，减少骨量丢失。
Conclusion: Nylestriol can inhibit expression of IL 6 mRNA, reduce osteoclastic bone resorption and decrease loss of bone mass.
双链断裂得不到修复，细胞将会死亡或发生染色体断裂、丢失，若是错误修复将导致基因突变或基因组不稳定，增加癌症的风险度。
If not repaired, the breakage can result in lethality or chromosome breakage, and if misrepaired, it can cause mutation, gene instability and the increased rate of tumorigenesis.
方法用比较基因组杂交技术(CGH)检测17例原发性NPC遗传物质的增多和丢失情况。
Methods Comparative genomic hybridization (CGH) was performed on 17 primary NPC biopsy specimens to find out any gain or loss of genetic material.
目的目前细菌定量检测提取细菌基因组多采用裂解法，此方法在提取基因组过程中部分基因组丢失。
Objective at present, the cracking method is often used when genome is extracted in quantification detection of bacteria.
目的目前细菌定量检测提取细菌基因组多采用裂解法，此方法在提取基因组过程中部分基因组丢失。
Objective at present, the cracking method is often used when genome is extracted in quantification detection of bacteria.
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