糖尿病大鼠有157种基因下调，100种基因上调，部分基因与胰岛素抵抗、糖脂代谢相关。
In diabetic rats, 157 genes were down-regulated and 100 genes up-regulated. Some of these genes were related to insulin resistance, glucose and lipid metabolism.
设备丰富笼中的老鼠表现微前炎症基因下调，而与抗炎过程相关的基因上调，蛋白降解，胆固醇被结合。
Enriched mice exhibited down-regulation of pro-inflammatory genes but up-regulation of genes related to anti-inflammatory processes, protein degradation and cholesterol binding.
你可以想象在同样的静脉中这些基因功能的丧失，你能想到在什么情况下你想下调免疫应答，比如在移植中。
In the same vein that you can imagine the loss of function of these genes, you can think of situations where you'd like to turn down the immune response, like in transplantation.
方法采用减式杂交技术筛选大肠癌下调基因。
Method Subtractive hybridization technique was employed to screen down regulated genes of colorectal cancer.
已有研究显示，RNA干扰下调肝癌形成相关基因的表达能有效抑制肝癌细胞的生长。
It has been reported the growth of liver cancer can be effectively controlled by specific gene silencing by RNAi.
它在鼻咽癌细胞和组织中表达明显下调，过表达BRD7基因可抑制鼻咽癌细胞的生长和细胞周期的进程。
It is obviously down-regulated in nasopharyngeal carcinoma (NPC) cells and tissues. Over expression of BRD7 in NPC cells can inhibit cell proliferation and cell cycle progression.
在人类多种恶性肿瘤尤其是胃癌中发现RUNX3基因表达缺失或下调。
The expression deficiency or down regulation of RUNX3 gene was detected in many malignant tumors especially in gastric cancer.
上调的主要是与适应性免疫相关的基因，下调的主要是与固有免疫相关的基因。
The up-regulated genes were mainly associated with adaptive immunity, while the down-regulated genes were associated with innate immunity.
结果芯片结果显示实验组已知功能差异表达基因有16条。其中下调基因有13条，4条与内分泌调控密切相关。
Results 16 identified genes expressed differently, including 13 down-regulated in which 4 were related to endocrine regulation.
这种抵抗可能与下调炎症基因表达的蛋白质有关。
This resistance may be related to proteins that down-regulate the expression of proinflammatory genes.
明确毒液能够下调菜粉蝶蛹清道夫受体基因的表达，并能抑制蛹血细胞的吞噬反应。
Venom could down-regulate the expression level of scavenger receptor gene, and inhibit the phagocytosis of pupal hemocytes.
经过分类分析，下调基因，主要可以分为五个功能类：蛋白质降解、RNA转录调控、细胞壁合成降解、激酶受体和肽运输。
The down-regulated genes can be divided in five classes:protein degradation, RNA transcription, cell wall synthesis and degradation, kinase receptor and peptide transport.
通过对数据库的搜索，发现SRZ基因在植物中广泛存在，并且水稻和拟南芥中，至少有一种类型的非生物胁迫可以显著下调SRZ的表达。
Database searches showed SRZ genes were widely distributed among plant species and their expressions in rice and Arabidopsis were significantly down-regulated by at least one type of abiotic stresses.
目的筛选胃癌下调基因组，发现新的胃癌下调基因。
Objective To screen down regulated genes and find down regulated novel genes in gastric cancer.
伴强迫人格与无强迫人格的强迫症患者COMT基因表达水平分别下调14%和56%；
The rates of COMT gene expression down-regulation in OCD patients with OCPD and ones without OCPD were 14%and 56%respectively.
我们对其中一个下调非常明显的S100A9基因进行了研究。
We further studied one of these down-regulated genes, S100A9.
结论：肠淋巴管结扎干预休克肺损伤的机制与上调或下调上述相关基因的表达有关。
CONCLUSION: the results indicate that the mechanism of mesenteric lymph ligation alleviating the lung injury after shock is related to up or down regulation of the above genes.
真核细胞翻译延伸因子2基因的表达水平显著下调。
Expression of the gene of eukaryotic translation elongation factor 2 could be down-regulated by E-36 protein.
结果基因芯片分析显示，HGC27细胞的64对核修复相关基因中，12对基因表达水平下调至0.5以下，6对基因表达水平上调至2倍以上。
Results The cDNA microarray results indicated that 12 out of 64 DNA repair related genes in HGC27 cells were down-regulated (inferior to 0.5 fold) and 6 genes was up-regulated (superior to 2 folds).
克隆到两个胃癌下调的新基因片段。
结果与对照组相比，干预组醛糖还原酶基因表达下调。
Results compared with the control group, the aldose reductase gene was down-regulated in the captopril intervention group.
结果：发现13种基因表达上调，没有得到下调基因。
Results: After analyzed, the data showed that there were 13 up-regulated genes, but no down-regulated gene.
结果：芯片结果显示实验组已知功能差异表达基因有16条，其中下调基因有13条，5条与物质能量代谢调控密切相关。
Results: 16 identified genes expressed differently, including 13 down-regulated in which 5 were related to substance and energy metabolism.
下调的基因主要是免疫球蛋白基因。
目的探讨MAL基因表达下调与食管癌病理分期、组织学分级的相关性。
Objective to explore the relevance between MAL gene expression, clinical stage and histologic grade of esophagus cancer.
结果共得到76条差异表达基因，上调基因71条，下调基因5条。
Results There were 76 differently expressed genes, 71 up-regulated genes and 5 down-regulated genes.
结果显示：（1）在急性高血糖情况下有521个基因上调，92个下调，急性低血糖情况下294个上调，464个下调；
The results indicated: 1) 521 genes up-regulated and 92 genes down-regulated under acute hyperglycemia, while 294 genes up-regulated and 464 down-regulated under acute hypoglycemia;
实时荧光定量PCR结果表明，该基因在受到条锈菌诱导下，在亲和组合中表达趋势明显下调，而在非亲合组合中的表达趋势比较稳定。
The results of real-time PCR analysis revealed that TAFFC transcripts were steady in incompatible interaction of wheat and stripe rust, whereas down-regulated in compatible interaction.
结果研究发现有143条基因在给药组中发生上调，101条基因发生了下调。
Results The obtained results showed that 143 genes revealed up-regulation and 101 genes showed down-regulation.
结果研究发现有143条基因在给药组中发生上调，101条基因发生了下调。
Results The obtained results showed that 143 genes revealed up-regulation and 101 genes showed down-regulation.
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