讨论了网格技术在药物研发领域的应用,药物研发不仅需要大量的计算资源,还需要一个信息交互集成的环境,使得研发过程各个方面的人员都能参与进来。
Drug discovery needs not only a great number of computing resources but also an environment for information exchange and aggregation, so that experts of all aspects can join during the process.
大量用于实验的动物生活不健康可能导致研究人员结果误判。 没有意识到这一点将导致治疗性药物研发继续在错误的轨道上进行。
Failure torecognize that many laboratory animals live unhealthy lives may be leadingresearchers to misinterpret their findings, potentially misdirecting efforts todevelop theraputic drugs.
如果研究人员在人类身上能找到类似的基因通路,也许可以研发出能有效治愈糖尿病的药物。
If researchers can identify a similar genetic pathway in humans, they may be able to develop drugs to effectively switch off diabetes.
在培养皿中制造毛细胞的方法将有助于科学家们发现促进听力的分子,也可用于刺激新的毛细胞生长的药物研发。
The method of creating hair cells in a dish will also allow scientists to discover molecules that enable hearing. And it will offer a way to screen for drugs that spur the growth of new hair cells.
因此过去20年,注意力一直集中在研发那些能将淀粉样蛋白斑从被感染的大脑中除掉的药物。
For the past two decades, therefore, most attention has been given to developing drugs that will remove amyloid plaques from an affected brain.
传统的治疗老年痴呆症的药物研发思路仅仅集中在淀粉样β蛋白的累积上,Nixon博士说。
Traditional drug development in Alzheimer's disease is taking too narrow an approach by focusing intensively on the buildup of amyloid beta-protein in the brain, Dr. Nixon says.
专家们在文中写道:这项研究揭示了一种新型蛋白转运装置的属性,因此为抗疟药物研发者提供了一个新的靶点。
"This study reveals the identity of a novel protein trafficking apparatus... and hence, provides an 'Achilles heel' for anti-malaria drug developers," they wrote.
煹“如果能研发一种应对在暴饮暴食的情况下阻止神经元免受伤害的药物,那么它将有利于避免肥胖的出现。”
Iff new medicines can be designed that limit neuron injury during overeating, they may be effective in combating the obesity epidemic.
这项对抗头痛的战役在许多面向如火如荼地进行着,从脑部化学的研究到原本为其他目的研发但可能有效控制偏头痛的药物都有。
The battle rages on many fronts, from research into brain chemistry to drugs developed for other USES that may be effective in controlling migraines.
在我们思考应用这些细胞治疗疾病之前需要首先扫除这些障碍,但是我们现在可以马上评估其能否作为药物研发的工具。
All these hurdles need to be overcome first before we can think about using the cells to treat disease, but we can start immediately to evaluate them as a tool for drug discovery.
简单、直接、自动化的淀粉浓度检测手段在食品、生化研究以及药物研发中受到了广泛应用。
Simple, direct and automation-ready procedures for measuring starch concentrations find wide applications in food, biochemical research and drug discovery.
随着正电子发射计算机断层显像技术(PET)的研发,PET 药物在肿瘤科学研究及临床应用中具有越来越重要的作用。
With the research and development of the PET techniques, the PET radiopharmaceuticals in oncology has played more and more important role in the tumor science study and clinical application.
FDA认识到药物基因组学的重要性并且鼓励其在药品研发中使用。
FDA recognizes the importance of pharmacogenomics and encourages its use in drug development.
它是细胞活动的重要指标,并且在研究和药物研发中已被用作一种细胞活性和细胞毒性的检测方法。
It is a key indicator of cellular activity and has been utilized as a measure of cell viability and cytotoxicity in research and drug discovery.
因此,在骨质疏松药物研发的过程中,以测定骨质量为主要目的的生物力学实验就显得尤为重要,且不能简单地被骨密度测定、骨组织形态学等等实验方法所取代。
Biomechanical experimental methods, one of whose main aims was to determine the bony quality, couldn't been superseded by the bone densitometry, the histomorphology of bony tissues, and so on.
现对ADP受体阻滞剂在抗血小板形成药物中的重要地位、研究进展和开发前景进行综述,为该类药物的研发提供依据。
This paper summarizes research developments and offers information on ADP receptors antagonists to provide evidence for further research and development.
在药物的研发过程中需对其质量进行系统、深入的研究,制订出科学、合理、可行的质量标准。
The scientific, reasonable and feasible specification should be established through thoroughly systematic research of the drugs.
近年来定量药理学中涉及的模型化和仿真预测在新药研发、治疗药物监测和临床个体化用药等方面得到了广泛的重视和研究。
Pharmacometrics has been widely valued for its utility of modeling and simulation in drug research and development, therapeutic drug monitoring and individualized therapy.
对这些转运蛋白的研究使人们能深入地解析药物在血脑脊液屏障上的动态,更有效地调控药物转运行为,指导脑靶向与非脑靶向药物的研发设计。
Study on these transporters could attribute to elucidate the action of the drug at the BCSFB, regulate the drug transport behavior and guide the research & d…
对这些转运蛋白的研究使人们能深入地解析药物在血脑脊液屏障上的动态,更有效地调控药物转运行为,指导脑靶向与非脑靶向药物的研发设计。
Study on these transporters could attribute to elucidate the action of the drug at the BCSFB, regulate the drug transport behavior and guide the research & d…
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