目的:观察半胱氨酸蛋白酶3在局灶性脑缺血再灌注不同时间、灶周皮质的动态时空变化。
AIM: To investigate the spatiotemporal change of caspase-3 at different time in perifocal cortex after focal cerebral ischemia and reperfusion.
目的研究血红素氧合酶1 (HO 1)及血红素氧合酶2 (HO 2)在局灶性脑缺血中的作用。
Objective To study the different role of heme oxygenase-1 (HO-1) and heme oxygenase-2 (HO-2) protein during permanent focal cerebral ischemia in rats.
方法:采用线栓法引起大鼠局灶性脑缺血模型,在缺血后进行再灌注,测定脑梗死面积并进行神经缺陷评分及观察病理组织学改变。
Methods: to make the model of cerebral ischemia and after restoration of blood flow with thread embolism, and measure the area of cerebral infarction and observe cerebral pathologic change.
结论局灶性脑缺血后,调节NO生成量在适当范围,可以达到保护、防止神经细胞进一步损伤的目的。
Conclusion in the process of focal cerebral ischemia and reperfusion, regulating the quantity of NO in the propriety range may protect and avoid purpose of neuronal cell injury.
应用猫局灶性脑缺血模型,利用计算机控制的激光多普勒血流计,持续监测猫脑不同位置在脑缺血时的血流变化。
The purpose was to observe the changes of cerebral blood flow at different position using the model of the cats with brain ischemia.
目的:研究大鼠局灶性脑缺血不同缺血时间皮质半暗带和中心区淀粉样前体蛋白(APP)在转录水平表达规律。
Aim: To investigate the changes of amyloid precursor protein (APP) transcriptional level at different ischemic times in rats' ischemic penumbra and core of cortices.
目的研究P-选择素和L-选择素在大鼠局灶性脑缺血再灌注后的表达规律,探讨P-选择素和L-选择素在脑缺血再灌注损伤中的作用。
Objective To evaluate the expression of P-selectin and L-selectin in rat focal cerebral ischemia-reperfusion. To study the effect of P-selectin and L-selectin in cerebral ischemia-reperfusion injury.
目的研究P-选择素和L-选择素在大鼠局灶性脑缺血再灌注后的表达规律,探讨P-选择素和L-选择素在脑缺血再灌注损伤中的作用。
Objective To evaluate the expression of P-selectin and L-selectin in rat focal cerebral ischemia-reperfusion. To study the effect of P-selectin and L-selectin in cerebral ischemia-reperfusion injury.
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