方法：HA为固体滴定物。
由于妥布霉素固体颗粒在常用滴定溶剂中的溶解度不大，采用常规的卡氏容量法难以快速精确的确定其水含量。
As for the poor solubility of tobramycin crystalline product in working medium used in volumetric Karl Fischer titration, two new methods for the water content determination were investigated.
由于妥布霉素固体颗粒在常用滴定溶剂中的溶解度不大，采用常规的卡氏容量法难以快速精确的确定其水含量。
As for the poor solubility of tobramycin crystalline product in working medium used in volumetric Karl Fischer titration, two new methods for the water content determination were investigated.
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