几项临床试验开展了噻唑烷二酮类药物预防糖尿病的研究。
There are several trials on prevention of diabetes with TZDs.
噻唑烷二酮类药物是一类新的治疗2型糖尿病和胰岛素抵抗的药物。
Thiazolidinediones (TZDs) are a new class of agents commonly used for the treatment of patients with type 2 diabetes or insulin resistance.
噻唑烷二酮类药物的应用存在一些问题，因为这类药物有一些副作用。
Thiazolodinediones are a problem because they seem to have some side effects associated with them.
噻唑烷二酮类药物是上世纪九十年代发明的，现被用于治疗2型糖尿病。
The drugs were introduced in the 1990s and are used to treat type 2 diabetes.
更令人烦恼的是，这已经引发了所有噻唑烷二酮类药物和所有PPAR方面药物的使用问题。
Even more worrisome, this has called into question the use of all thiazolidinediones and all PPAR-directed agents.
吡格列酮是一种噻唑烷二酮类药物，可以改善胰岛素敏感性并且改善2型糖尿病的糖脂代谢。
Pioglitazone is a thiazolidinedione that ameliorates insulin resistance and improves glucose and lipid metabolism in type 2 diabetes mellitus.
依照这一研究，患有糖尿病的男性在同时服用髓袢利尿药和噻唑烷二酮类药物时也会增加骨折的危险。
Men with diabetes taking both loop diuretics and TZDs may also be at increased risk of fractures, according to the research.
最近关于罗格列酮（一种噻唑烷二酮类药物）的研究显示该药对一般糖尿病患者心血管有不利影响产生。
Recent studies have associated rosiglitazone, a thiazolidinedione drug, with adverse cardiovascular outcomes in the general population with diabetes.
目的：罗格列酮等噻唑烷二酮类药物具有降低血压，延缓心血管疾病进展的作用，但具体机制不甚清楚。
Objective: The thiazolidinediones such as rosiglitazone have been reported to yield cardiovascular benefits in patients by a mechanism that is not completely understood.
这一结果特别令人感兴趣，因为男性，单独使用髓袢利尿药或噻唑烷二酮类药物，都不能形成显著的危害。
This result is particularly interesting because in men, loop diuretics or TZDs alone did not confer significant risks.
一项新的研究显示患有糖尿病的绝经妇女在服用噻唑烷二酮类药物，包括匹格列酮与罗格列酮时，会增加骨折的危险。
A new study has revealed that postmenopausal women with diabetes taking thiazolidinediones (TZDS), including rosiglitazone and pioglitazone, may be at increased risk for fractures.
但目前还没有已发表的探讨噻唑烷二酮类药物用于青少年2型糖尿病治疗的研究，这类药物会导致许多不良反应，特别是体重增加。
But there are no published studies on thiazolidinediones for treatment of type 2 diabetes in youth, and the drugs have substantial side effects, especially weight gain.
文迪雅，作为一种众所周知的经典药物-噻唑烷二酮类，用于与二甲双胍或磺脲类药物降低2性糖尿病患者的学堂。
Avandia, one of a class of medications known as thiazolidinediones, is used to lower blood sugar in patients with type 2 diabetes in combination with two other drugs, metformin and sulfonylurea.
文迪雅，作为一种众所周知的经典药物-噻唑烷二酮类，用于与二甲双胍或磺脲类药物降低2性糖尿病患者的学堂。
Avandia, one of a class of medications known as thiazolidinediones, is used to lower blood sugar in patients with type 2 diabetes in combination with two other drugs, metformin and sulfonylurea.
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